5,7-Bis(1-benzothio-phen-2-yl)-2,3-dihydro-thieno[3,4-b][1,4]dioxine.

In the title compound, C(22)H(14)O(2)S(3), the dioxane ring is disordered over two sites [site occupancies = 0.623 (3) and 0.377 (3)]; both components adopt half-chair conformations. The two benzothio-phene ring systems are asymmetrically twisted away from the attached thio-phene ring [dihedral angles = 20.57 (3) and 6.70 (3)°] and are oriented at an angle of 26.83 (3)°. No significant hydrogen bonding or π-π inter-actions are observed in the crystal structure.

Related literature

For related literature, see: Cohen et al. (1977 ▶); Csaszar & Morvay (1983 ▶); Dzhurayev et al. (1992 ▶); EI-Maghraby et al. (1984 ▶); Gewald et al. (1996 ▶); Lakshmi et al. (1985 ▶); Pellis & West (1968 ▶). For the synthesis, see: Amaladass et al. (2007 ▶).

Experimental

Crystal data

C22H14O2S3

M = 406.51

Monoclinic,

a = 16.1602 (5) Å

b = 8.3524 (3) Å

c = 14.1814 (4) Å

β = 107.428 (2)°

V = 1826.28 (10) Å3

Z = 4

Mo Kα radiation

μ = 0.42 mm−1

T = 293 (2) K

0.15 × 0.13 × 0.10 mm

Data collection

Bruker Kappa APEXII area-detector diffractometer

Absorption correction: none

26571 measured reflections

7059 independent reflections

4551 reflections with I > 2σ(I)

R int = 0.028

Refinement

R[F 2 > 2σ(F 2)] = 0.044

wR(F 2) = 0.142

S = 0.99

7059 reflections

251 parameters

3 restraints

H-atom parameters constrained

Δρmax = 0.61 e Å−3

Δρmin = −0.43 e Å−3

Data collection: APEX2 (Bruker, 2004 ▶); cell refinement: APEX2; data reduction: SAINT (Bruker, 2004 ▶); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ▶); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008 ▶); molecular graphics: PLATON (Spek, 2003 ▶); software used to prepare material for publication: SHELXL97 and PARST (Nardelli, 1995 ▶).

Crystal structure: contains datablocks I, global. DOI: 10.1107/S1600536808012324/ci2577sup1.cif

Structure factors: contains datablocks I. DOI: 10.1107/S1600536808012324/ci2577Isup2.hkl

Additional supplementary materials: crystallographic information; 3D view; checkCIF report

C22H14O2S3	F000 = 840
Mr = 406.51	Dx = 1.478 Mg m−3
Monoclinic, P21/c	Mo Kα radiation λ = 0.71073 Å
Hall symbol: -P 2ybc	Cell parameters from 4583 reflections
a = 16.1602 (5) Å	θ = 2.8–33.8º
b = 8.3524 (3) Å	µ = 0.42 mm−1
c = 14.1814 (4) Å	T = 293 (2) K
β = 107.428 (2)º	Block, light green
V = 1826.28 (10) Å3	0.15 × 0.13 × 0.10 mm
Z = 4

Bruker Kappa APEXII area-detector diffractometer	4551 reflections with I > 2σ(I)
Radiation source: fine-focus sealed tube	Rint = 0.028
Monochromator: graphite	θmax = 33.4º
T = 293(2) K	θmin = 2.8º
ω and φ scans	h = −24→24
Absorption correction: none	k = −12→10
26571 measured reflections	l = −21→19
7059 independent reflections

Refinement on F2	Secondary atom site location: difference Fourier map
Least-squares matrix: full	Hydrogen site location: inferred from neighbouring sites
R[F2 > 2σ(F2)] = 0.044	H-atom parameters constrained
wR(F2) = 0.143	w = 1/[σ2(Fo2) + (0.0749P)2 + 0.444P] where P = (Fo2 + 2Fc2)/3
S = 0.99	(Δ/σ)max < 0.001
7059 reflections	Δρmax = 0.61 e Å−3
251 parameters	Δρmin = −0.43 e Å−3
3 restraints	Extinction correction: none
Primary atom site location: structure-invariant direct methods

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

	x	y	z	Uiso*/Ueq	Occ. (<1)
C1	−0.28863 (11)	0.4031 (2)	−0.01894 (14)	0.0499 (4)
H1	−0.2949	0.3569	−0.0804	0.060*
C2	−0.35994 (12)	0.4572 (3)	0.00498 (16)	0.0578 (5)
H2	−0.4145	0.4490	−0.0412	0.069*
C3	−0.35223 (12)	0.5241 (2)	0.09694 (18)	0.0597 (5)
H3	−0.4017	0.5590	0.1115	0.072*
C4	−0.27258 (12)	0.5395 (2)	0.16681 (16)	0.0533 (4)
H4	−0.2674	0.5837	0.2285	0.064*
C5	−0.19971 (10)	0.48665 (19)	0.14227 (13)	0.0419 (3)
C6	−0.20599 (10)	0.41809 (19)	0.05007 (12)	0.0400 (3)
C7	−0.12301 (10)	0.3765 (2)	0.03966 (13)	0.0430 (3)
H7	−0.1153	0.3287	−0.0164	0.052*
C8	−0.05619 (10)	0.41564 (19)	0.12239 (11)	0.0374 (3)
C9	0.03586 (9)	0.39615 (18)	0.13747 (11)	0.0364 (3)
C10	0.07580 (9)	0.29651 (18)	0.08760 (11)	0.0357 (3)
C11A	0.08383 (17)	0.1322 (5)	−0.0432 (2)	0.0502 (8)	0.623 (3)
H11A	0.0937	0.2125	−0.0881	0.060*	0.623 (3)
H11B	0.0543	0.0420	−0.0820	0.060*	0.623 (3)
C12A	0.16828 (17)	0.0790 (3)	0.0260 (2)	0.0485 (6)	0.623 (3)
H12A	0.1574	−0.0005	0.0707	0.058*	0.623 (3)
H12B	0.2022	0.0283	−0.0117	0.058*	0.623 (3)
C11B	0.0915 (3)	0.0850 (5)	−0.0061 (4)	0.0502 (8)	0.377 (3)
H11C	0.0623	0.0295	−0.0670	0.060*	0.377 (3)
H11D	0.1046	0.0059	0.0464	0.060*	0.377 (3)
C12B	0.1754 (3)	0.1472 (7)	−0.0147 (2)	0.0485 (6)	0.377 (3)
H12C	0.2092	0.0622	−0.0318	0.058*	0.377 (3)
H12D	0.1658	0.2309	−0.0643	0.058*	0.377 (3)
C13	0.16712 (9)	0.30254 (18)	0.12251 (11)	0.0365 (3)
C14	0.19858 (9)	0.40987 (19)	0.19816 (11)	0.0362 (3)
C15	0.28812 (9)	0.44752 (19)	0.24924 (11)	0.0352 (3)
C16	0.36041 (10)	0.3755 (2)	0.23942 (12)	0.0416 (3)
H16	0.3587	0.2893	0.1973	0.050*
C17	0.43920 (10)	0.44442 (19)	0.29966 (11)	0.0380 (3)
C18	0.52506 (11)	0.4008 (2)	0.30912 (15)	0.0512 (4)
H18	0.5366	0.3159	0.2725	0.061*
C19	0.59199 (11)	0.4840 (2)	0.37253 (15)	0.0521 (4)
H19	0.6489	0.4558	0.3781	0.062*
C20	0.57576 (11)	0.6105 (2)	0.42876 (14)	0.0483 (4)
H20	0.6220	0.6645	0.4722	0.058*
C21	0.49236 (11)	0.6563 (2)	0.42076 (13)	0.0469 (4)
H21	0.4816	0.7414	0.4578	0.056*
C22	0.42398 (9)	0.57260 (19)	0.35592 (11)	0.0374 (3)
O1	0.03162 (7)	0.19777 (15)	0.01304 (9)	0.0476 (3)
O2	0.21883 (7)	0.21067 (15)	0.08407 (9)	0.0467 (3)
S1	0.11311 (2)	0.50367 (5)	0.22588 (3)	0.04068 (11)
S2	0.31369 (3)	0.60648 (5)	0.33305 (3)	0.04677 (12)
S3	−0.09260 (3)	0.49989 (6)	0.21576 (3)	0.04834 (13)

	U11	U22	U33	U12	U13	U23
C1	0.0415 (8)	0.0560 (10)	0.0467 (9)	−0.0071 (7)	0.0047 (7)	0.0089 (8)
C2	0.0338 (8)	0.0654 (12)	0.0667 (12)	−0.0030 (8)	0.0037 (8)	0.0162 (10)
C3	0.0355 (8)	0.0585 (11)	0.0856 (15)	0.0057 (8)	0.0188 (9)	0.0054 (10)
C4	0.0418 (9)	0.0515 (10)	0.0684 (12)	0.0037 (7)	0.0192 (8)	−0.0063 (9)
C5	0.0336 (7)	0.0393 (8)	0.0529 (9)	−0.0002 (6)	0.0131 (6)	0.0001 (7)
C6	0.0355 (7)	0.0390 (8)	0.0445 (8)	−0.0019 (6)	0.0103 (6)	0.0061 (6)
C7	0.0352 (7)	0.0473 (9)	0.0470 (8)	0.0003 (6)	0.0132 (6)	0.0079 (7)
C8	0.0331 (7)	0.0393 (8)	0.0401 (7)	0.0004 (5)	0.0114 (5)	0.0008 (6)
C9	0.0316 (6)	0.0395 (8)	0.0378 (7)	−0.0003 (5)	0.0098 (5)	0.0003 (6)
C10	0.0332 (6)	0.0376 (7)	0.0353 (7)	−0.0025 (5)	0.0086 (5)	−0.0015 (6)
C11A	0.0450 (11)	0.070 (2)	0.0369 (17)	−0.0104 (12)	0.0148 (13)	−0.0198 (14)
C12A	0.0432 (11)	0.0540 (18)	0.0478 (15)	0.0009 (11)	0.0128 (11)	−0.0150 (11)
C11B	0.0450 (11)	0.070 (2)	0.0369 (17)	−0.0104 (12)	0.0148 (13)	−0.0198 (14)
C12B	0.0432 (11)	0.0540 (18)	0.0478 (15)	0.0009 (11)	0.0128 (11)	−0.0150 (11)
C13	0.0340 (7)	0.0378 (8)	0.0383 (7)	0.0019 (5)	0.0116 (5)	−0.0024 (6)
C14	0.0317 (6)	0.0395 (8)	0.0368 (7)	−0.0001 (5)	0.0095 (5)	−0.0018 (6)
C15	0.0338 (7)	0.0372 (7)	0.0349 (7)	−0.0016 (5)	0.0106 (5)	−0.0026 (6)
C16	0.0363 (7)	0.0423 (8)	0.0461 (8)	−0.0022 (6)	0.0122 (6)	−0.0089 (7)
C17	0.0338 (7)	0.0402 (8)	0.0411 (7)	−0.0023 (6)	0.0130 (6)	−0.0008 (6)
C18	0.0364 (8)	0.0547 (10)	0.0645 (11)	0.0013 (7)	0.0181 (7)	−0.0109 (8)
C19	0.0328 (8)	0.0577 (11)	0.0659 (11)	−0.0027 (7)	0.0153 (7)	−0.0001 (9)
C20	0.0360 (8)	0.0509 (10)	0.0535 (9)	−0.0103 (7)	0.0066 (7)	0.0011 (8)
C21	0.0402 (8)	0.0486 (9)	0.0495 (9)	−0.0081 (7)	0.0096 (7)	−0.0090 (7)
C22	0.0324 (7)	0.0401 (8)	0.0394 (7)	−0.0029 (6)	0.0103 (5)	−0.0005 (6)
O1	0.0379 (6)	0.0534 (7)	0.0495 (6)	−0.0055 (5)	0.0100 (5)	−0.0169 (5)
O2	0.0355 (5)	0.0520 (7)	0.0520 (6)	0.0028 (5)	0.0121 (5)	−0.0160 (5)
S1	0.03413 (18)	0.0475 (2)	0.0409 (2)	−0.00031 (15)	0.01199 (14)	−0.00916 (16)
S2	0.03469 (19)	0.0501 (2)	0.0539 (2)	−0.00041 (16)	0.01081 (16)	−0.01687 (18)
S3	0.0361 (2)	0.0621 (3)	0.0464 (2)	0.00043 (17)	0.01175 (16)	−0.01084 (19)

C1—C2	1.372 (3)	C11B—O1	1.434 (2)
C1—C6	1.405 (2)	C11B—C12B	1.490 (3)
C1—H1	0.93	C11B—H11C	0.97
C2—C3	1.390 (3)	C11B—H11D	0.97
C2—H2	0.93	C12B—O2	1.465 (3)
C3—C4	1.375 (3)	C12B—H12C	0.97
C3—H3	0.93	C12B—H12D	0.97
C4—C5	1.396 (2)	C13—O2	1.3627 (18)
C4—H4	0.93	C13—C14	1.373 (2)
C5—C6	1.403 (2)	C14—C15	1.445 (2)
C5—S3	1.7361 (17)	C14—S1	1.7325 (15)
C6—C7	1.435 (2)	C15—C16	1.358 (2)
C7—C8	1.375 (2)	C15—S2	1.7470 (15)
C7—H7	0.93	C16—C17	1.425 (2)
C8—C9	1.447 (2)	C16—H16	0.93
C8—S3	1.7496 (16)	C17—C22	1.400 (2)
C9—C10	1.372 (2)	C17—C18	1.401 (2)
C9—S1	1.7318 (15)	C18—C19	1.371 (3)
C10—O1	1.3622 (18)	C18—H18	0.93
C10—C13	1.410 (2)	C19—C20	1.395 (3)
C11A—O1	1.433 (2)	C19—H19	0.93
C11A—C12A	1.490 (3)	C20—C21	1.373 (2)
C11A—H11A	0.97	C20—H20	0.93
C11A—H11B	0.97	C21—C22	1.395 (2)
C12A—O2	1.467 (2)	C21—H21	0.93
C12A—H12A	0.97	C22—S2	1.7365 (15)
C12A—H12B	0.97
C2—C1—C6	119.47 (18)	C12B—C11B—H11D	107.8
C2—C1—H1	120.3	H11C—C11B—H11D	107.2
C6—C1—H1	120.3	O2—C12B—C11B	103.6 (3)
C1—C2—C3	121.26 (17)	O2—C12B—H12C	111.0
C1—C2—H2	119.4	C11B—C12B—H12C	111.0
C3—C2—H2	119.4	O2—C12B—H12D	111.0
C4—C3—C2	121.00 (18)	C11B—C12B—H12D	111.0
C4—C3—H3	119.5	H12C—C12B—H12D	109.0
C2—C3—H3	119.5	O2—C13—C14	123.51 (13)
C3—C4—C5	117.93 (19)	O2—C13—C10	122.83 (13)
C3—C4—H4	121.0	C14—C13—C10	113.66 (13)
C5—C4—H4	121.0	C13—C14—C15	127.90 (14)
C4—C5—C6	122.04 (16)	C13—C14—S1	109.79 (11)
C4—C5—S3	126.46 (15)	C15—C14—S1	122.30 (12)
C6—C5—S3	111.48 (12)	C16—C15—C14	127.96 (14)
C5—C6—C1	118.29 (16)	C16—C15—S2	111.78 (11)
C5—C6—C7	112.69 (14)	C14—C15—S2	120.24 (11)
C1—C6—C7	129.00 (17)	C15—C16—C17	113.66 (14)
C8—C7—C6	111.96 (15)	C15—C16—H16	123.2
C8—C7—H7	124.0	C17—C16—H16	123.2
C6—C7—H7	124.0	C22—C17—C18	118.81 (15)
C7—C8—C9	127.53 (14)	C22—C17—C16	111.87 (13)
C7—C8—S3	112.65 (12)	C18—C17—C16	129.32 (16)
C9—C8—S3	119.82 (11)	C19—C18—C17	119.69 (17)
C10—C9—C8	127.84 (14)	C19—C18—H18	120.2
C10—C9—S1	109.84 (11)	C17—C18—H18	120.2
C8—C9—S1	122.33 (12)	C18—C19—C20	120.82 (16)
O1—C10—C9	123.31 (13)	C18—C19—H19	119.6
O1—C10—C13	122.97 (13)	C20—C19—H19	119.6
C9—C10—C13	113.69 (13)	C21—C20—C19	120.79 (16)
O1—C11A—C12A	108.9 (2)	C21—C20—H20	119.6
O1—C11A—H11A	109.9	C19—C20—H20	119.6
C12A—C11A—H11A	109.9	C20—C21—C22	118.62 (17)
O1—C11A—H11B	109.9	C20—C21—H21	120.7
C12A—C11A—H11B	109.9	C22—C21—H21	120.7
H11A—C11A—H11B	108.3	C21—C22—C17	121.27 (15)
O2—C12A—C11A	113.1 (2)	C21—C22—S2	127.40 (13)
O2—C12A—H12A	109.0	C17—C22—S2	111.34 (11)
C11A—C12A—H12A	109.0	C10—O1—C11A	113.88 (16)
O2—C12A—H12B	109.0	C10—O1—C11B	108.6 (3)
C11A—C12A—H12B	109.0	C13—O2—C12B	114.2 (2)
H12A—C12A—H12B	107.8	C13—O2—C12A	109.99 (15)
O1—C11B—C12B	117.9 (4)	C9—S1—C14	92.98 (7)
O1—C11B—H11C	107.8	C22—S2—C15	91.35 (7)
C12B—C11B—H11C	107.8	C5—S3—C8	91.20 (8)
O1—C11B—H11D	107.8
C6—C1—C2—C3	−1.2 (3)	C15—C16—C17—C18	179.46 (17)
C1—C2—C3—C4	0.6 (3)	C22—C17—C18—C19	−0.2 (3)
C2—C3—C4—C5	0.4 (3)	C16—C17—C18—C19	−179.69 (18)
C3—C4—C5—C6	−0.7 (3)	C17—C18—C19—C20	0.8 (3)
C3—C4—C5—S3	177.48 (15)	C18—C19—C20—C21	−1.0 (3)
C4—C5—C6—C1	0.1 (2)	C19—C20—C21—C22	0.7 (3)
S3—C5—C6—C1	−178.33 (13)	C20—C21—C22—C17	−0.1 (3)
C4—C5—C6—C7	178.37 (16)	C20—C21—C22—S2	179.76 (14)
S3—C5—C6—C7	−0.02 (18)	C18—C17—C22—C21	−0.2 (2)
C2—C1—C6—C5	0.8 (2)	C16—C17—C22—C21	179.43 (15)
C2—C1—C6—C7	−177.15 (17)	C18—C17—C22—S2	179.96 (13)
C5—C6—C7—C8	−0.8 (2)	C16—C17—C22—S2	−0.43 (18)
C1—C6—C7—C8	177.27 (16)	C9—C10—O1—C11A	166.6 (2)
C6—C7—C8—C9	−177.96 (15)	C13—C10—O1—C11A	−15.2 (3)
C6—C7—C8—S3	1.29 (18)	C9—C10—O1—C11B	−166.3 (3)
C7—C8—C9—C10	−20.4 (3)	C13—C10—O1—C11B	11.9 (3)
S3—C8—C9—C10	160.45 (14)	C12A—C11A—O1—C10	43.7 (3)
C7—C8—C9—S1	159.31 (14)	C12A—C11A—O1—C11B	−39.6 (5)
S3—C8—C9—S1	−19.89 (18)	C12B—C11B—O1—C10	−46.7 (5)
C8—C9—C10—O1	0.2 (3)	C12B—C11B—O1—C11A	60.0 (5)
S1—C9—C10—O1	−179.48 (12)	C14—C13—O2—C12B	−160.2 (3)
C8—C9—C10—C13	−178.15 (15)	C10—C13—O2—C12B	19.4 (3)
S1—C9—C10—C13	2.15 (17)	C14—C13—O2—C12A	163.91 (19)
O1—C11A—C12A—O2	−62.3 (4)	C10—C13—O2—C12A	−16.4 (2)
O1—C11B—C12B—O2	64.4 (6)	C11B—C12B—O2—C13	−46.1 (4)
O1—C10—C13—O2	0.4 (2)	C11B—C12B—O2—C12A	43.8 (2)
C9—C10—C13—O2	178.81 (14)	C11A—C12A—O2—C13	47.1 (3)
O1—C10—C13—C14	−179.88 (14)	C11A—C12A—O2—C12B	−56.9 (4)
C9—C10—C13—C14	−1.5 (2)	C10—C9—S1—C14	−1.77 (12)
O2—C13—C14—C15	0.8 (3)	C8—C9—S1—C14	178.51 (13)
C10—C13—C14—C15	−178.84 (15)	C13—C14—S1—C9	0.95 (13)
O2—C13—C14—S1	179.79 (12)	C15—C14—S1—C9	179.96 (13)
C10—C13—C14—S1	0.11 (17)	C21—C22—S2—C15	−179.22 (16)
C13—C14—C15—C16	−6.2 (3)	C17—C22—S2—C15	0.63 (13)
S1—C14—C15—C16	174.99 (14)	C16—C15—S2—C22	−0.69 (13)
C13—C14—C15—S2	171.90 (13)	C14—C15—S2—C22	−179.06 (13)
S1—C14—C15—S2	−6.92 (19)	C4—C5—S3—C8	−177.68 (17)
C14—C15—C16—C17	178.79 (15)	C6—C5—S3—C8	0.63 (13)
S2—C15—C16—C17	0.57 (19)	C7—C8—S3—C5	−1.11 (13)
C15—C16—C17—C22	−0.1 (2)	C9—C8—S3—C5	178.20 (13)