| Literature DB >> 21198172 |
Jeffrey W Oliver1, David J Stolarski, Gary D Noojin, Harvey M Hodnett, Corey A Harbert, Kurt J Schuster, Michael F Foltz, Semih S Kumru, Clarence P Cain, C J Finkeldei, Gavin D Buffington, Isaac D Noojin, Robert J Thomas.
Abstract
A series of experiments are conducted in vivo using Yucatan mini-pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1940-nm continuous-wave thulium fiber laser irradiation. Experiments employ exposure durations from 10 ms to 10 s and beam diameters of approximately 4.8 to 18 mm. Thermal imagery data provide a time-dependent surface temperature response from the laser. A damage endpoint of minimally visible effect is employed to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of optical-thermal interaction. Results are compared with current exposure limits for laser safety. It is concluded that exposure limits should be based on data representative of large-beam exposures, where effects of radial diffusion are minimized for longer-duration damage thresholds.Entities:
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Year: 2010 PMID: 21198172 DOI: 10.1117/1.3523622
Source DB: PubMed Journal: J Biomed Opt ISSN: 1083-3668 Impact factor: 3.170