Literature DB >> 2119002

A critical review of permeabilized cell systems for studying mammalian DNA repair.

S Keeney1, S Linn.   

Abstract

Permeabilized cell systems have proven valuable for studies of the enzymology of mammalian DNA repair and this review will summarize and contrast the different systems used to this end. Results from permeable cell studies will be reviewed which pertain to 3 questions of DNA repair: the role(s) of ATP, DNA polymerase enzymology, and the isolation of repair factors by in vitro correction of repair-defective cells.

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Year:  1990        PMID： 2119002     DOI： 10.1016/0921-8777(90)90008-s

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  8 in total

1.  DNA polymerase beta is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide.

Authors:  P Fortini; B Pascucci; F Belisario; E Dogliotti
Journal:  Nucleic Acids Res       Date:  2000-08-15       Impact factor: 16.971

2.  Characterization of the DNA polymerase requirement of human base excision repair.

Authors:  K Nealon; I D Nicholl; M K Kenny
Journal:  Nucleic Acids Res       Date:  1996-10-01       Impact factor: 16.971

3.  The kinetics and mechanism of repair of UV induced DNA damage in mammalian cells. The use of 'caged' nucleotides and electroporation to study short time course events in DNA repair.

Authors:  R A Meldrum; W S Meaking; C W Wharton
Journal:  Nucleic Acids Res       Date:  1994-04-11       Impact factor: 16.971

4.  Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C.

Authors:  K O Aley; R O Messing; D Mochly-Rosen; J D Levine
Journal:  J Neurosci       Date:  2000-06-15       Impact factor: 6.167

5.  Enzymatic activities involved in the DNA resynthesis step of nucleotide excision repair are firmly attached to chromatin.

Authors:  K Bouayadi; A van der Leer-van Hoffen; A S Balajee; A T Natarajan; A A van Zeeland; L H Mullenders
Journal:  Nucleic Acids Res       Date:  1997-03-01       Impact factor: 16.971

6.  Properties of damage-dependent DNA incision by nucleotide excision repair in human cell-free extracts.

Authors:  P Calsou; B Salles
Journal:  Nucleic Acids Res       Date:  1994-11-25       Impact factor: 16.971

7.  Purification of PCNA as a nucleotide excision repair protein.

Authors:  A F Nichols; A Sancar
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

8.  Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

Authors:  J C Huang; D L Svoboda; J T Reardon; A Sancar
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205
  8 in total

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