Literature DB >> 21189684

Insights into the structural basis of RNA recognition by STAR domain proteins.

Sean P Ryder1, Francesca Massi.   

Abstract

STAR proteins regulate diverse cellular processes and control numerous developmental events. They function at the post-transcriptional level by regulating the stability, sub-cellular distribution, alternative splicing, or translational efficiency of specific mRNA targets. Significant effort has been expended to define the determinants of RNA recognition by STAR proteins, in hopes of identifying new mRNA targets that contribute their role in cellular metabolism and development. This work has lead to the extensive biochemical characterization ofthe nucleotide sequence specificity of a handful of STAR proteins. In contrast, little structural information is available to analyze the molecular basis of sequence specific RNA recognition by this protein family. This chapter reviews the relevant literature on STAR domain protein structure and provides insights into how these proteins discriminate between different RNA sequences.

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Year:  2010        PMID： 21189684      PMCID： PMC5034770          DOI： 10.1007/978-1-4419-7005-3_3

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  64 in total

1.  Two isoforms of the Drosophila RNA binding protein, how, act in opposing directions to regulate tendon cell differentiation.

Authors:  H Nabel-Rosen; G Volohonsky; A Reuveny; R Zaidel-Bar; T Volk
Journal:  Dev Cell       Date:  2002-02       Impact factor: 12.270

2.  Structure of Pumilio reveals similarity between RNA and peptide binding motifs.

Authors:  T A Edwards; S E Pyle; R P Wharton; A K Aggarwal
Journal:  Cell       Date:  2001-04-20       Impact factor: 41.582

3.  Solution structure and backbone dynamics of the KH-QUA2 region of the Xenopus STAR/GSG quaking protein.

Authors:  Mahon L Maguire; Gulin Guler-Gane; Daniel Nietlispach; Andrew R C Raine; Aaron M Zorn; Nancy Standart; R William Broadhurst
Journal:  J Mol Biol       Date:  2005-04-29       Impact factor: 5.469

4.  Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia.

Authors:  Karolina Aberg; Peter Saetre; Niclas Jareborg; Elena Jazin
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-25       Impact factor: 11.205

5.  Recruitment of Nanos to hunchback mRNA by Pumilio.

Authors:  J Sonoda; R P Wharton
Journal:  Genes Dev       Date:  1999-10-15       Impact factor: 11.361

6.  Function of quaking in myelination: regulation of alternative splicing.

Authors:  Jiang I Wu; Robyn B Reed; Paula J Grabowski; Karen Artzt
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-26       Impact factor: 11.205

7.  Genomic organization and expression analysis of the mouse qkI locus.

Authors:  T Kondo; T Furuta; K Mitsunaga; T A Ebersole; M Shichiri; J Wu; K Artzt; K Yamamura; K Abe
Journal:  Mamm Genome       Date:  1999-07       Impact factor: 2.957

8.  Structural basis for recognition of the intron branch site RNA by splicing factor 1.

Authors:  Z Liu; I Luyten; M J Bottomley; A C Messias; S Houngninou-Molango; R Sprangers; K Zanier; A Krämer; M Sattler
Journal:  Science       Date:  2001-11-02       Impact factor: 47.728

9.  Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA.

Authors:  S Arning; P Grüter; G Bilbe; A Krämer
Journal:  RNA       Date:  1996-08       Impact factor: 4.942

10.  Translational regulation of tra-2 by its 3' untranslated region controls sexual identity in C. elegans.

Authors:  E B Goodwin; P G Okkema; T C Evans; J Kimble
Journal:  Cell       Date:  1993-10-22       Impact factor: 41.582
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  6 in total

1.  Increased sensitivity and accuracy of a single-stranded DNA splint-mediated ligation assay (sPAT) reveals poly(A) tail length dynamics of developmentally regulated mRNAs.

Authors:  Ryuji Minasaki; David Rudel; Christian R Eckmann
Journal:  RNA Biol       Date:  2014-02-10       Impact factor: 4.652

2.  The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells.

Authors:  Yunling Wang; Gillian Vogel; Zhenbao Yu; Stéphane Richard
Journal:  Mol Cell Biol       Date:  2013-01-14       Impact factor: 4.272

3.  Nuclear T-STAR protein expression correlates with HER2 status, hormone receptor negativity and prolonged recurrence free survival in primary breast cancer and decreased cancer cell growth in vitro.

Authors:  Sandra Sernbo; Carl A K Borrebaeck; Mathias Uhlén; Karin Jirström; Sara Ek
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240

4.  Overexpression of miR-29a reduces the oncogenic properties of glioblastoma stem cells by downregulating Quaking gene isoform 6.

Authors:  Zhuo Xi; Ping Wang; Yixue Xue; Chao Shang; Xiaobai Liu; Jun Ma; Zhiqing Li; Zhen Li; Min Bao; Yunhui Liu
Journal:  Oncotarget       Date:  2017-04-11

5.  Screening protein--single stranded RNA complexes by NMR spectroscopy for structure determination.

Authors:  Jaelle N Foot; Mikael Feracci; Cyril Dominguez
Journal:  Methods       Date:  2013-10-01       Impact factor: 3.608

6.  Structural and functional implications of the QUA2 domain on RNA recognition by GLD-1.

Authors:  Gerrit M Daubner; Anneke Brümmer; Cristina Tocchini; Stefan Gerhardy; Rafal Ciosk; Mihaela Zavolan; Frédéric H-T Allain
Journal:  Nucleic Acids Res       Date:  2014-05-16       Impact factor: 16.971
  6 in total

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