OBJECTIVE: Determine if World Trade Center (WTC) disaster responders had lower lung function and higher bronchodilator responsiveness than those with respiratory symptoms and conditions. METHODS: We evaluated cardinal respiratory symptoms (dyspnea, wheezing, dry cough, productive cough) and determined the difference in FEV1, FVC, and bronchodilator responsiveness. RESULTS: All respiratory symptoms were associated with a lower FEV1 and FVC, and a larger bronchodilator response. Responders reporting chronic productive cough, starting during WTC work and persisting, had a mean FEV1 109 mL lower than those without chronic persistent cough; their odds of having abnormally low FEV1 was 1.40 times higher; and they were 1.65 times as likely to demonstrate bronchodilator responsiveness. CONCLUSIONS: Responders reporting chronic persistent cough, wheezing or dyspnea at first medical examination were more likely to have lower lung function and bronchodilator responsiveness.
OBJECTIVE: Determine if World Trade Center (WTC) disaster responders had lower lung function and higher bronchodilator responsiveness than those with respiratory symptoms and conditions. METHODS: We evaluated cardinal respiratory symptoms (dyspnea, wheezing, dry cough, productive cough) and determined the difference in FEV1, FVC, and bronchodilator responsiveness. RESULTS: All respiratory symptoms were associated with a lower FEV1 and FVC, and a larger bronchodilator response. Responders reporting chronic productive cough, starting during WTC work and persisting, had a mean FEV1 109 mL lower than those without chronic persistent cough; their odds of having abnormally low FEV1 was 1.40 times higher; and they were 1.65 times as likely to demonstrate bronchodilator responsiveness. CONCLUSIONS: Responders reporting chronic persistent cough, wheezing or dyspnea at first medical examination were more likely to have lower lung function and bronchodilator responsiveness.
Authors: Jackie Soo; Mayris P Webber; Charles B Hall; Hillel W Cohen; Theresa M Schwartz; Kerry J Kelly; David J Prezant Journal: Chest Date: 2012-11 Impact factor: 9.410
Authors: Juan P Wisnivesky; Susan L Teitelbaum; Andrew C Todd; Paolo Boffetta; Michael Crane; Laura Crowley; Rafael E de la Hoz; Cornelia Dellenbaugh; Denise Harrison; Robin Herbert; Hyun Kim; Yunho Jeon; Julia Kaplan; Craig Katz; Stephen Levin; Ben Luft; Steven Markowitz; Jacqueline M Moline; Fatih Ozbay; Robert H Pietrzak; Moshe Shapiro; Vansh Sharma; Gwen Skloot; Steven Southwick; Lori A Stevenson; Iris Udasin; Sylvan Wallenstein; Philip J Landrigan Journal: Lancet Date: 2011-09-03 Impact factor: 202.731