Literature DB >> 21185178

6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors.

Johnny Y Nagasawa1, Jenny Song, Huanming Chen, Hong-Woo Kim, Julie Blazel, Samedy Ouk, Bettina Groschel, Virginia Borges, Voon Ong, Li-Tain Yeh, Jean-Luc Girardet, Jean-Michel Vernier, Anneke K Raney, Anthony B Pinkerton.   

Abstract

SAR studies on the quinolone carboxylic acid class of HIV-1 integrase inhibitors focused on improving the metabolic stability and led to the discovery of 27 and 38. Copyright Â
© 2010 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21185178     DOI： 10.1016/j.bmcl.2010.11.108

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  HIV Drug Resistance and the Advent of Integrase Inhibitors.

Authors:  Peter K Quashie; Thibault Mesplède; Mark A Wainberg
Journal:  Curr Infect Dis Rep       Date:  2013-02       Impact factor: 3.725

2.  Functional evaluation of variants of unknown significance in the BRCA2 gene identified in genetic testing.

Authors:  Marie Heczkova; Eva Machackova; Peter Macinga; Eike Gallmeier; Monika Cahova; Julius Spicak; Milan Jirsa; Lenka Foretova; Tomas Hucl
Journal:  Cancer Biol Ther       Date:  2019-01-13       Impact factor: 4.742

Review 3.  Novel therapeutic strategies targeting HIV integrase.

Authors:  Peter K Quashie; Richard D Sloan; Mark A Wainberg
Journal:  BMC Med       Date:  2012-04-12       Impact factor: 8.775

Review 4.  The Need for Development of New HIV-1 Reverse Transcriptase and Integrase Inhibitors in the Aftermath of Antiviral Drug Resistance.

Authors:  Mark A Wainberg
Journal:  Scientifica (Cairo)       Date:  2012-12-31

Review 5.  Progress in HIV-1 Integrase Inhibitors: A Review of their Chemical Structure Diversity.

Authors:  Zahra Hajimahdi; Afshin Zarghi
Journal:  Iran J Pharm Res       Date:  2016       Impact factor: 1.696

6.  N-(7-Methyl-1,8-naphthyridin-2-yl)acetamide-acetic acid (1/1).

Authors:  Gao-Zhang Gou; Rui Ma; Qing-Di Zhou; Shao-Ming Chi
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-03-06
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.