Literature DB >> 21183631

Novel structural elements within the nonproteolytic clostridium botulinum type F toxin gene cluster.

N Dover1, J R Barash, K K Hill, J C Detter, S S Arnon.   

Abstract

We sequenced for the first time the complete neurotoxin gene cluster of a nonproteolytic Clostridium botulinum type F. The neurotoxin gene cluster contained a novel gene arrangement that, compared to other C. botulinum neurotoxin gene clusters, lacked the regulatory botR gene and contained an intergenic is element between its orfX2 and orfX3 genes.

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Year:  2010        PMID: 21183631      PMCID: PMC3067269          DOI: 10.1128/AEM.02422-10

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  16 in total

1.  Genetic diversity among Botulinum Neurotoxin-producing clostridial strains.

Authors:  K K Hill; T J Smith; C H Helma; L O Ticknor; B T Foley; R T Svensson; J L Brown; E A Johnson; L A Smith; R T Okinaka; P J Jackson; J D Marks
Journal:  J Bacteriol       Date:  2006-11-17       Impact factor: 3.490

2.  Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes.

Authors:  Nir Dover; Jason R Barash; Stephen S Arnon
Journal:  J Clin Microbiol       Date:  2009-05-06       Impact factor: 5.948

3.  Genomics. Genome project standards in a new era of sequencing.

Authors:  P S G Chain; D V Grafham; R S Fulton; M G Fitzgerald; J Hostetler; D Muzny; J Ali; B Birren; D C Bruce; C Buhay; J R Cole; Y Ding; S Dugan; D Field; G M Garrity; R Gibbs; T Graves; C S Han; S H Harrison; S Highlander; P Hugenholtz; H M Khouri; C D Kodira; E Kolker; N C Kyrpides; D Lang; A Lapidus; S A Malfatti; V Markowitz; T Metha; K E Nelson; J Parkhill; S Pitluck; X Qin; T D Read; J Schmutz; S Sozhamannan; P Sterk; R L Strausberg; G Sutton; N R Thomson; J M Tiedje; G Weinstock; A Wollam; J C Detter
Journal:  Science       Date:  2009-10-09       Impact factor: 47.728

Review 4.  Botulinum toxin as a biological weapon: medical and public health management.

Authors:  S S Arnon; R Schechter; T V Inglesby; D A Henderson; J G Bartlett; M S Ascher; E Eitzen; A D Fine; J Hauer; M Layton; S Lillibridge; M T Osterholm; T O'Toole; G Parker; T M Perl; P K Russell; D L Swerdlow; K Tonat
Journal:  JAMA       Date:  2001-02-28       Impact factor: 56.272

5.  Regulation of toxin and bacteriocin gene expression in Clostridium by interchangeable RNA polymerase sigma factors.

Authors:  Bruno Dupuy; Stéphanie Raffestin; Susana Matamouros; Nagraj Mani; Michel R Popoff; Abraham L Sonenshein
Journal:  Mol Microbiol       Date:  2006-05       Impact factor: 3.501

6.  Sequence diversity of genes encoding botulinum neurotoxin type F.

Authors:  Brian H Raphael; Mallory J Choudoir; Carolina Lúquez; Rafael Fernández; Susan E Maslanka
Journal:  Appl Environ Microbiol       Date:  2010-05-28       Impact factor: 4.792

7.  PCR assay for differentiating between Group I (proteolytic) and Group II (nonproteolytic) strains of Clostridium botulinum.

Authors:  Elias Dahlsten; Hannu Korkeala; Panu Somervuo; Miia Lindström
Journal:  Int J Food Microbiol       Date:  2008-02-21       Impact factor: 5.277

8.  Neurotoxin gene clusters in Clostridium botulinum type Ab strains.

Authors:  Carolina Lúquez; Brian H Raphael; Susan E Maslanka
Journal:  Appl Environ Microbiol       Date:  2009-08-14       Impact factor: 4.792

9.  Analysis of neurotoxin cluster genes in Clostridium botulinum strains producing botulinum neurotoxin serotype A subtypes.

Authors:  Mark J Jacobson; Guangyun Lin; Brian Raphael; Joanne Andreadis; Eric A Johnson
Journal:  Appl Environ Microbiol       Date:  2008-03-07       Impact factor: 4.792

10.  Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.

Authors:  Theresa J Smith; Karen K Hill; Brian T Foley; John C Detter; A Christine Munk; David C Bruce; Norman A Doggett; Leonard A Smith; James D Marks; Gary Xie; Thomas S Brettin
Journal:  PLoS One       Date:  2007-12-05       Impact factor: 3.240

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  5 in total

1.  Arrangement of the Clostridium baratii F7 toxin gene cluster with identification of a σ factor that recognizes the botulinum toxin gene cluster promoters.

Authors:  Nir Dover; Jason R Barash; Julianne N Burke; Karen K Hill; John C Detter; Stephen S Arnon
Journal:  PLoS One       Date:  2014-05-22       Impact factor: 3.240

2.  Clostridium botulinum strain Af84 contains three neurotoxin gene clusters: bont/A2, bont/F4 and bont/F5.

Authors:  Nir Dover; Jason R Barash; Karen K Hill; Karen W Davenport; Hazuki Teshima; Gary Xie; Stephen S Arnon
Journal:  PLoS One       Date:  2013-04-12       Impact factor: 3.240

3.  The type F6 neurotoxin gene cluster locus of group II clostridium botulinum has evolved by successive disruption of two different ancestral precursors.

Authors:  Andrew T Carter; Sandra C Stringer; Martin D Webb; Michael W Peck
Journal:  Genome Biol Evol       Date:  2013       Impact factor: 3.416

4.  Genomic and physiological variability within Group II (non-proteolytic) Clostridium botulinum.

Authors:  Sandra C Stringer; Andrew T Carter; Martin D Webb; Ewelina Wachnicka; Lisa C Crossman; Mohammed Sebaihia; Michael W Peck
Journal:  BMC Genomics       Date:  2013-05-16       Impact factor: 3.969

5.  Comparative genomic analyses reveal broad diversity in botulinum-toxin-producing Clostridia.

Authors:  Charles H D Williamson; Jason W Sahl; Theresa J Smith; Gary Xie; Brian T Foley; Leonard A Smith; Rafael A Fernández; Miia Lindström; Hannu Korkeala; Paul Keim; Jeffrey Foster; Karen Hill
Journal:  BMC Genomics       Date:  2016-03-03       Impact factor: 3.969

  5 in total

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