BACKGROUND: the measurement of nasal inspiratory pressure, known as the sniff test, was developed as a new test of inspiratory muscle strength, mainly used in neuromuscular conditions. The test is easy to be performed and noninvasive. Despite the clinical importance of assessment of nasal inspiratory pressure a national equipment is not available to assess it. OBJECTIVES: to compare a national with a foreign manovacuometer in assessing the nasal inspiratory pressure (sniff test) in healthy subjects. METHODS:18 subjects were evaluated (age 21.44 ± 2.8 years, BMI 23.4 ± 2.5 kg/m² , FVC 102.1 ±1 0.3% pred, FEV1 98.4 ± 1% pred). We performed two measures of nasal inspiratory pressure using two different manovacuometer: a national and a foreign. All subjects performed the tests at the same time of day, in different days being the order of the testes established randomly. It was used the paired t test, Pearson correlation and the Bland-Altman plots for statistical analysis considering a 5% significance level. RESULTS: The averages observed for the two measures of nasal pressures were 125 ± 42.4 cmH2O for the foreign equipment, and 131.7 ± 2 8.7 cmH2O for the national equipment. The Pearson correlation showed significant correlation between the means with a coefficient of r=0.63. The t test showed no significant differences between both measurements (p>0,05). The BIAS ± SD found in Bland-Altman plot analysis was 7 cmH2O with limits of agreement between -57.5 cmH2O and 71.5 cmH2O. CONCLUSION: the results suggest that the national electronic device is feasible and safe to the sniff test measurement in healthy subjects.
RCT Entities:
BACKGROUND: the measurement of nasal inspiratory pressure, known as the sniff test, was developed as a new test of inspiratory muscle strength, mainly used in neuromuscular conditions. The test is easy to be performed and noninvasive. Despite the clinical importance of assessment of nasal inspiratory pressure a national equipment is not available to assess it. OBJECTIVES: to compare a national with a foreign manovacuometer in assessing the nasal inspiratory pressure (sniff test) in healthy subjects. METHODS: 18 subjects were evaluated (age 21.44 ± 2.8 years, BMI 23.4 ± 2.5 kg/m² , FVC 102.1 ±1 0.3% pred, FEV1 98.4 ± 1% pred). We performed two measures of nasal inspiratory pressure using two different manovacuometer: a national and a foreign. All subjects performed the tests at the same time of day, in different days being the order of the testes established randomly. It was used the paired t test, Pearson correlation and the Bland-Altman plots for statistical analysis considering a 5% significance level. RESULTS: The averages observed for the two measures of nasal pressures were 125 ± 42.4 cmH2O for the foreign equipment, and 131.7 ± 2 8.7 cmH2O for the national equipment. The Pearson correlation showed significant correlation between the means with a coefficient of r=0.63. The t test showed no significant differences between both measurements (p>0,05). The BIAS ± SD found in Bland-Altman plot analysis was 7 cmH2O with limits of agreement between -57.5 cmH2O and 71.5 cmH2O. CONCLUSION: the results suggest that the national electronic device is feasible and safe to the sniff test measurement in healthy subjects.
Authors: Renata Andrade da Cunha; Daniele Andrade da Cunha; Roberta Borba Assis; Luciana Ângelo Bezerra; Hilton Justino da Silva Journal: Int Arch Otorhinolaryngol Date: 2013-11-05