Literature DB >> 21180718

Synthesis and characterization of small circular double-stranded RNAs.

Naoko Abe1, Hiroshi Abe, Takahito Ohshiro, Yuko Nakashima, Mizuo Maeda, Yoshihiro Ito.   

Abstract

Small circular double-stranded RNAs (dsRNAs) were synthesized. The structural analysis by atomic force microscopy gave direct images for the interpretation of the structural strain present in circular dsRNAs. Finally, we demonstrated that circular dsRNA caused RNAi effect in cells.

Mesh:

Substances:

Year:  2010        PMID: 21180718     DOI: 10.1039/c0cc04551a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  In vitro circularization of RNA.

Authors:  Sabine Müller; Bettina Appel
Journal:  RNA Biol       Date:  2016-09-26       Impact factor: 4.652

2.  Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing.

Authors:  Hartmut Jahns; Rohan Degaonkar; Peter Podbevsek; Swati Gupta; Anna Bisbe; Krishna Aluri; John Szeto; Pawan Kumar; Sarah LeBlanc; Tim Racie; Christopher R Brown; Adam Castoreno; Dale C Guenther; Vasant Jadhav; Martin A Maier; Janez Plavec; Martin Egli; Muthiah Manoharan; Ivan Zlatev
Journal:  Nucleic Acids Res       Date:  2021-10-11       Impact factor: 16.971

3.  Circular siRNAs for Reducing Off-Target Effects and Enhancing Long-Term Gene Silencing in Cells and Mice.

Authors:  Liangliang Zhang; Duanwei Liang; Changmai Chen; Yuan Wang; Gubu Amu; Jiali Yang; Lijia Yu; Ivan J Dmochowski; Xinjing Tang
Journal:  Mol Ther Nucleic Acids       Date:  2017-12-19       Impact factor: 8.886

4.  Generation of siRNA Nanosheets for Efficient RNA Interference.

Authors:  Hyejin Kim; Jae Sung Lee; Jong Bum Lee
Journal:  Sci Rep       Date:  2016-04-28       Impact factor: 4.379

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.