Literature DB >> 21179045

Phenalinolactones A-D, terpenoglycoside antibiotics from Streptomyces sp. Tü 6071.

Klaus Gebhardt1, Sven W Meyer, Jochen Schinko, Gerhard Bringmann, Axel Zeeck, Hans-Peter Fiedler.   

Abstract

Four new terpenoglycoside antibiotics, phenalinolactones A-D were isolated from Streptomyces sp. Tü 6071. The structures were elucidated on the basis of detailed NMR and MS analyses. Phenalinolactones combine a diterpenoid tricycle, a 2,3,6-trideoxysugar, a pyrrole-carboxylic acid and an uncommonly oxidized unsaturated γ-lactone in a unique manner. Phenalinolactones show an inhibitory activity against gram-positive bacteria.

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Year:  2010        PMID: 21179045     DOI: 10.1038/ja.2010.165

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  5 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  Discovery of the Tiancilactone Antibiotics by Genome Mining of Atypical Bacterial Type II Diterpene Synthases.

Authors:  Liao-Bin Dong; Jeffrey D Rudolf; Ming-Rong Deng; Xiaohui Yan; Ben Shen
Journal:  Chembiochem       Date:  2018-05-27       Impact factor: 3.164

3.  Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules.

Authors:  Roland D Kersten; Nadine Ziemert; David J Gonzalez; Brendan M Duggan; Victor Nizet; Pieter C Dorrestein; Bradley S Moore
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-04       Impact factor: 11.205

Review 4.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

5.  Tryptorubin A: A Polycyclic Peptide from a Fungus-Derived Streptomycete.

Authors:  Thomas P Wyche; Antonio C Ruzzini; Laura Schwab; Cameron R Currie; Jon Clardy
Journal:  J Am Chem Soc       Date:  2017-09-06       Impact factor: 15.419

  5 in total

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