| Literature DB >> 2117315 |
C Schmid1, A Beham, P Steindorfer, L Auböck, F Waltner.
Abstract
We report the second case of a malignant paraganglioma of the stomach in a 56-year-old female patient. However, our case is the first investigated by immunohistochemistry and electron-microscopy. The tumour was characterized immunohistochemically by the presence of neurofilament protein, glial fibrillary acidic protein, S-100 protein, neuron-specific enolase, chromogranin A, ACTH, leu-enkephalin and vasoactive intestinal polypeptide, and ultrastructurally by demonstration of neurosecretory granules and paranuclear intermediate filament whorls. Despite massive metastatic spread in the abdominal cavity, the patient is still alive 4 years after initial diagnosis.Entities:
Mesh:
Year: 1990 PMID: 2117315 DOI: 10.1007/bf01600143
Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN: 0174-7398