| Literature DB >> 21172183 |
Marco Oliver Schunter1, Thorsten Walles, Peter Fritz, Uta Meyding-Lamadé, Klaus-Peter Thon, Klaus Fellermann, Eduard Friedrich Stange, Wolfram Lamadé.
Abstract
In patients with inflammatory bowel disease herpes simplex virus infection has been described as a major cause of morbidity and mortality, especially in immunocompromised individuals. Here we present the case of a 35-year old woman with an exacerbation of ulcerative colitis caused by herlpes simplex virus infection (HSV-2). The diagnosis was confirmed histologically following subtotal colectomy. After intravenous treatment with aciclovir for 2 weeks postoperative hematochezia stopped. Herpes simplex virus colitis is a rare but potentially fatal complication of immunosuppressive treatment in patients with inflammatory bowel disease. Prompt diagnosis and efficient antiviral therapy are mandatory to improve prognosis.Entities:
Year: 2007 PMID： 21172183 DOI： 10.1016/j.crohns.2007.06.004
Source DB: PubMed Journal: J Crohns Colitis ISSN： 1873-9946 Impact factor: 9.071