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Literature DB >> 2117170

New aspects of isocyanate asthma.

Abstract

Air concentration of isocyanates are associated with the frequency of induced diseases. Asthma, bronchitis and rhinitis, chronic obstructive lung disease, and allergic alveolitis, respectively, were observed in exposed workers. Inhalation challenge tests with isocyanates found some 14% of symptomatic persons immunologically sensitized. At and above current threshold limit values (10 ppb) there is a risk of lung function deterioration also in asymptomatic workers.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1990 PMID： 2117170 DOI： 10.1007/bf02718184

Source DB: PubMed Journal: Lung ISSN： 0341-2040 Impact factor: 2.584

13 in total

1. Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine.

Authors: C Vogelmeier; X Baur; G Fruhmann
Journal: Int Arch Occup Environ Health Date: 1991 Impact factor: 3.015

2. Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI.

Authors: A W Musk; J M Peters; L DiBerardinis; R L Murphy
Journal: J Occup Med Date: 1982-10

3. Five-year longitudinal study of workers employed in a new toluene diisocyanate manufacturing plant.

Authors: J E Diem; R N Jones; D J Hendrick; H W Glindmeyer; V Dharmarajan; B T Butcher; J E Salvaggio; H Weill
Journal: Am Rev Respir Dis Date: 1982-09

4. The temporal relationship between increases in airway responsiveness to histamine and late asthmatic responses induced by occupational agents.

Authors: S R Durham; B J Graneek; R Hawkins; A J Taylor
Journal: J Allergy Clin Immunol Date: 1987-02 Impact factor: 10.793

5. Effects of chronic exposure to diisocyanates.

Authors: Q T Pham; D Teculescu; C Meyer-Bisch; J M Mur
Journal: Bull Eur Physiopathol Respir Date: 1987 Nov-Dec

6. Detection of immunologically sensitized isocyanate workers by RAST and intracutaneous skin tests.

Authors: X Baur; M Dewair; G Fruhmann
Journal: J Allergy Clin Immunol Date: 1984-05 Impact factor: 10.793

7. Inhibition of acetylcholinesterase by diisocyanates and its spontaneous reactivation.

Authors: M Dewair; X Baur; R Mauermayer
Journal: Int Arch Occup Environ Health Date: 1983 Impact factor: 3.015

8. Pulmonary and immunologic evaluation of foundry workers exposed to methylene diphenyldiisocyanate (MDI).

Authors: G M Liss; D I Bernstein; D R Moller; J S Gallagher; R L Stephenson; I L Bernstein
Journal: J Allergy Clin Immunol Date: 1988-07 Impact factor: 10.793

9. Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease.

Authors: J M Peters; D H Wegman
Journal: Environ Health Perspect Date: 1975-06 Impact factor: 9.031

10. Sensory and pulmonary irritation of methyl isocyanate in mice and pulmonary irritation and possible cyanidelike effects of methyl isocyanate in guinea pigs.

Authors: Y Alarie; J S Ferguson; M F Stock; D A Weyel; M Schaper
Journal: Environ Health Perspect Date: 1987-06 Impact factor: 9.031

5 in total

New aspects of isocyanate asthma.

1. Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine.

2. Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI.

3. Five-year longitudinal study of workers employed in a new toluene diisocyanate manufacturing plant.

4. The temporal relationship between increases in airway responsiveness to histamine and late asthmatic responses induced by occupational agents.

5. Effects of chronic exposure to diisocyanates.

6. Detection of immunologically sensitized isocyanate workers by RAST and intracutaneous skin tests.

7. Inhibition of acetylcholinesterase by diisocyanates and its spontaneous reactivation.

8. Pulmonary and immunologic evaluation of foundry workers exposed to methylene diphenyldiisocyanate (MDI).

9. Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease.

10. Sensory and pulmonary irritation of methyl isocyanate in mice and pulmonary irritation and possible cyanidelike effects of methyl isocyanate in guinea pigs.

Review 1. Occupational asthma due to isocyanates.

2. Respiratory effects and skin allergy in workers exposed to tetrachloroisophthalonitrile.

3. Experimental study on respiratory sensitivity to inhaled toluene diisocyanate.

Review 4. Respiratory and other hazards of isocyanates.

5. Cellular and mediator profile in bronchoalveolar lavage of guinea pigs after toluene diisocyanate (TDI) exposure.