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Literature DB >> 170078

Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease.

Abstract

This paper describes our experience with the respiratory effects of TDI. Five respiratory reactions attributable to TDI are described with supporting evidence. The reactions are sensitization, irritation from overexposure, acute loss of ventilatory capacity, accelerated loss of pulmonary function and induction of a general asthmatic state. Evidence is presented that suggests a safe exposure level.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1975 PMID： 170078 PMCID： PMC1475208 DOI： 10.1289/ehp.751197

Source DB: PubMed Journal: Environ Health Perspect ISSN： 0091-6765 Impact factor: 9.031

15 in total

1. STUDIES OF VENTILATORY CAPACITY AND HISTAMINE RESPONSE DURING EXPOSURE TO ISOCYANATE VAPOUR IN POLYURETHANE FOAM MANUFACTURE.

Authors: B GANDEVIA
Journal: Br J Ind Med Date: 1963-07

2. PREDICTION VALUES FOR SCREENING TESTS OF PULMONARY FUNCTION.

Authors: B G FERRIS; D O ANDERSON; R ZICKMANTEL
Journal: Am Rev Respir Dis Date: 1965-02

3. The Veterans Administration-Army cooperative study of pulmonary function. I. Clinical spirometry in normal men.

Authors: R C KORY; R CALLAHAN; H G BOREN; J C SYNER
Journal: Am J Med Date: 1961-02 Impact factor: 4.965

4. Evolution of the ventilatory capacity in chronic bronchitis.

Authors: P Howard
Journal: Br Med J Date: 1967-08-12

5. A dose-response relationship in TDI workers.

Authors: D H Wegman; L D Pagnotto; L J Fine; J M Peters
Journal: J Occup Med Date: 1974-04

6. Environmental epidemiology. IV. Chronic respiratory disease in an industrial town: a nine-year follow-up study. Preliminary report.

Authors: I T Higgins; J C Gilson; B G Ferris; M E Waters; H Campbell; M W Higgins
Journal: Am J Public Health Nations Health Date: 1968-09

7. Course and prognosis of chronic obstructive lung disease. A prospective study of 200 patients.

Authors: B Burrows; R H Earle
Journal: N Engl J Med Date: 1969-02-20 Impact factor: 91.245

8. Ventilation studies on a normal population after a seven-year interval.

Authors: D Y Rosenzweig; J A Arkins; L G Schrock
Journal: Am Rev Respir Dis Date: 1966-07

9. Toluene di-isocyanate (TDI) toxicity.

Authors: H G BRUGSCH; H B ELKINS
Journal: N Engl J Med Date: 1963-02-14 Impact factor: 91.245

10. Acute respiratory effects in workers exposed to low levels of toluene diisocyanate (TDI).

Authors: J M Peters; R L Murphy; L D Pagnotto; W F Van Ganse
Journal: Arch Environ Health Date: 1968-05

12 in total

Review 1. New aspects of isocyanate asthma.

Authors: X Baur
Journal: Lung Date: 1990 Impact factor: 2.584

2. Chronic pulmonary function loss from exposure to toluene diisocyanate.

Authors: D H Wegman; J M Peters; L Pagnotto; L J Fine
Journal: Br J Ind Med Date: 1977-08

3. [Intoxication due to dicyclohexyl-methane-4-4' diisocyanate exposure (author's transl)].

Authors: R Israeli; V Smirnov; M Sculsky
Journal: Int Arch Occup Environ Health Date: 1981 Impact factor: 3.015

4. Persistent reactive airway dysfunction syndrome after exposure to toluene diisocyanate.

Authors: J C Luo; K G Nelsen; A Fischbein
Journal: Br J Ind Med Date: 1990-04

Review 5. The potential impact of epidemiology on the prevention of occupational disease.

Authors: D H Wegman
Journal: Am J Public Health Date: 1992-07 Impact factor: 9.308

Review 6. Respiratory and other hazards of isocyanates.

Authors: X Baur; W Marek; J Ammon; A B Czuppon; B Marczynski; M Raulf-Heimsoth; H Roemmelt; G Fruhmann
Journal: Int Arch Occup Environ Health Date: 1994 Impact factor: 3.015

7. Amines: possible causative agents in the development of bronchial hyperreactivity in workers manufacturing polyurethanes from isocyanates.

Authors: L Belin; U Wass; G Audunsson; L Mathiasson
Journal: Br J Ind Med Date: 1983-08

8. Biomarkers predicting isocyanate-induced asthma.

Authors: Nami Shrestha Palikhe; Joo-Hee Kim; Hae-Sim Park
Journal: Allergy Asthma Immunol Res Date: 2010-07-29 Impact factor: 5.764

9. Occupational and environmental health hazards in the plastics industry.

Authors: R E Eckardt
Journal: Environ Health Perspect Date: 1976-10 Impact factor: 9.031

10. Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry.

Authors: James J Collins; Steve Anteau; Patrick R Conner; Laura D Cassidy; Brent Doney; Mei Lin Wang; Laura Kurth; Michael Carson; Don Molenaar; Carrie A Redlich; Eileen Storey
Journal: J Occup Environ Med Date: 2017-12 Impact factor: 2.162