Literature DB >> 21164348

Conservative treatment of acute appendicitis: heresy or an effective and acceptable alternative to surgery?

George H Sakorafas1, Aikaterini Mastoraki, Christos Lappas, Dimitrios Sampanis, Nikolaos Danias, Vassileios Smyrniotis.   

Abstract

For more than a century, emergency appendectomy has been a 'surgical dogma' in the management of acute appendicitis (AA). During recent decades, however, there is an increasing body of evidence suggesting that selected patients with AA could be treated conservatively. This approach has many advantages, including high success and low recurrence rates, reduced morbidity and mortality, less pain, shorter hospitalization and sick leave, and reduced costs. Despite that conservative management of AA cannot be used for all patients with AA (for example, in the presence of peritonitis), it could be preferred in a large percentage of patients with mild infection (as evidenced by clinical, laboratory, and imaging findings).

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Year:  2011        PMID: 21164348     DOI: 10.1097/MEG.0b013e32834233b6

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  9 in total

1.  Risk of perforation increases with delay in recognition and surgery for acute appendicitis.

Authors:  Dominic Papandria; Seth D Goldstein; Daniel Rhee; Jose H Salazar; Jamir Arlikar; Amany Gorgy; Gezzer Ortega; Yiyi Zhang; Fizan Abdullah
Journal:  J Surg Res       Date:  2012-12-27       Impact factor: 2.192

2.  Feasibility, acceptance, safety, and effectiveness of antibiotic therapy as alternative treatment approach to appendectomy in uncomplicated acute appendicitis.

Authors:  Daniela Prechal; Stefan Post; Ioanna Pechlivanidou; Ulrich Ronellenfitsch
Journal:  Int J Colorectal Dis       Date:  2019-09-12       Impact factor: 2.571

Review 3.  Acute appendicitis: what is the gold standard of treatment?

Authors:  Cesare Ruffolo; Alain Fiorot; Giulia Pagura; Michele Antoniutti; Marco Massani; Ezio Caratozzolo; Luca Bonariol; Francesco Calia di Pinto; Nicolò Bassi
Journal:  World J Gastroenterol       Date:  2013-12-21       Impact factor: 5.742

4.  The NOTA study: non-operative treatment for acute appendicitis: prospective study on the efficacy and safety of antibiotic treatment (amoxicillin and clavulanic acid) in patients with right sided lower abdominal pain.

Authors:  Gregorio Tugnoli; Eleonora Giorgini; Andrea Biscardi; Silvia Villani; Nicola Clemente; Gianluca Senatore; Filippo Filicori; Nicola Antonacci; Franco Baldoni; Carlo De Werra; Salomone Di Saverio
Journal:  BMJ Open       Date:  2011-02-23       Impact factor: 2.692

5.  Delayed appendectomy versus early appendectomy in the treatment of acute appendicitis: a retrospective study.

Authors:  Chang Sik Shin; Young Nam Roh; Jae Il Kim
Journal:  World J Emerg Surg       Date:  2014-01-21       Impact factor: 5.469

Review 6.  Case-based review: conservative management of appendicitis--are we delaying the inevitable?

Authors:  S Davies; A Peckham-Cooper; A Sverrisdottir
Journal:  Ann R Coll Surg Engl       Date:  2012-05       Impact factor: 1.891

7.  A prospective randomized controlled multicenter trial comparing antibiotic therapy with appendectomy in the treatment of uncomplicated acute appendicitis (APPAC trial).

Authors:  Hannu Paajanen; Juha M Grönroos; Tero Rautio; Pia Nordström; Markku Aarnio; Tuomo Rantanen; Saija Hurme; Kirsti Dean; Airi Jartti; Jukka-Pekka Mecklin; Juhani Sand; Paulina Salminen
Journal:  BMC Surg       Date:  2013-02-08       Impact factor: 2.102

8.  The necessity of nighttime appendectomies: Is appendicitis an emergency?

Authors:  Go Ohba; Koji Komori; Seiichi Hirobe
Journal:  Afr J Paediatr Surg       Date:  2020 Jan-Jun

9.  Laparoscopic Surgery and the debate on its safety during COVID-19 pandemic: A systematic review of recommendations.

Authors:  Michael El Boghdady; Beatrice Marianne Ewalds-Kvist
Journal:  Surgeon       Date:  2020-08-11       Impact factor: 2.632

  9 in total

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