Literature DB >> 21161205

Brown adipose tissue 18F-FDG uptake in pediatric PET/CT imaging.

Terence S Hong1, Amer Shammas, Martin Charron, Katherine A Zukotynski, Laura A Drubach, Ruth Lim.   

Abstract

Positron emission tomography (PET) using [F-18]2-fluoro-2-deoxyglucose (FDG) fused with CT ((18)F-FDG PET/CT) has been widely adopted in oncological imaging. However, it is known that benign lesions and other metabolically active tissues, such as brown adipose tissue (BAT), can accumulate (18)F-FDG, potentially resulting in false-positive interpretation. Previous studies have reported that (18)F-FDG uptake in BAT is more common in children than in adults. We illustrate BAT FDG uptake in various anatomical locations in children and adolescents. We also review what is known about the effects of patient-related physical attributes and environmental temperatures on BAT FDG uptake, and discuss methods used to reduce BAT FDG uptake on (18)F-FDG PET.

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Year:  2010        PMID： 21161205     DOI： 10.1007/s00247-010-1925-y

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN： 0301-0449


  35 in total

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