Literature DB >> 21160762

ERCP in acute pancreatitis: What takes place in routine clinical practice?

Armando Gabbrielli1, Raffaele Pezzilli, Generoso Uomo, Alessandro Zerbi, Luca Frulloni, Paolo De Rai, Laura Castoldi, Guido Costamagna, Claudio Bassi, Valerio Di Carlo.   

Abstract

AIM: To evaluate the data from a survey carried out in Italy regarding the endoscopic approach to acute pancreatitis in order to obtain a picture of what takes place after the release of an educational project on acute pancreatitis sponsored by the Italian Association for the Study of the Pancreas.
METHODS: Of the 1 173 patients enrolled in our survey, the most frequent etiological category was biliary forms (69.3%) and most patients had mild pancreatitis (85.8%).
RESULTS: 344/1 173 (29.3%) underwent endoscopic retrograde cholangiopancreatography (ERCP). The mean interval between the onset of symptoms and ERCP was 6.7 ± 5.0 d; only 89 examinations (25.9%) were performed within 72 h from the onset of symptoms. The main indications for ERCP were suspicion of common bile duct stones (90.3%), jaundice (44.5%), clinical worsening of acute pancreatitis (14.2%) and cholangitis (6.1%). Biliary and pancreatic ducts were visualized in 305 patients (88.7%) and in 93 patients (27.0%) respectively. The success rate in obtaining a cholangiogram was statistically higher (P = 0.003) in patients with mild acute pancreatitis (90.6%) than in patients with severe disease (72.2%). Biliary endoscopic sphincterotomy was performed in 295 of the 305 patients (96.7%) with no difference between mild and severe disease (P = 0.985). ERCP morbidity was 6.1% and mortality was 1.7%; the mortality was due to the complications of acute pancreatitis and not the endoscopic procedure.
CONCLUSION: The results of this survey, as with those carried out in other countries, indicate a lack of compliance with the guidelines for the indications for interventional endoscopy.

Entities:  

Keywords:  Acute pancreatitis; Data collection; Epidemiology, Endoscopic retrograde cholangiopancreatography

Year:  2010        PMID: 21160762      PMCID: PMC2999033          DOI: 10.4253/wjge.v2.i9.308

Source DB:  PubMed          Journal:  World J Gastrointest Endosc


  28 in total

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2.  Early ERCP in acute gallstone pancreatitis without cholangitis: a meta-analysis.

Authors:  Manley C Uy; Ma Lourdes O Daez; Peter P Sy; Virgilio P Banez; Wendell Z Espinosa; Marilyn C Talingdan-Te
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Review 3.  Systematic review of endoscopic ultrasonography versus endoscopic retrograde cholangiopancreatography for suspected choledocholithiasis.

Authors:  M S Petrov; T J Savides
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4.  The role of biliary obstruction in the pathogenesis of acute pancreatitis in the opossum.

Authors:  N Senninger; F G Moody; J C Coelho; D H Van Buren
Journal:  Surgery       Date:  1986-06       Impact factor: 3.982

5.  Controlled trial of urgent endoscopic retrograde cholangiopancreatography and endoscopic sphincterotomy versus conservative treatment for acute pancreatitis due to gallstones.

Authors:  J P Neoptolemos; D L Carr-Locke; N J London; I A Bailey; D James; D P Fossard
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6.  Endoscopic sphincterotomy in acute biliary pancreatitis: A question of anesthesiological risk.

Authors:  Raffaele Pezzilli
Journal:  World J Gastrointest Endosc       Date:  2009-10-15

7.  Effects of early ductal decompression in human biliary acute pancreatitis.

Authors:  R Pezzilli; P Billi; B Barakat; D Baroncini; N D'Imperio; F Miglio
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Review 8.  Early endoscopic retrograde cholangiopancreatography versus conservative management in acute biliary pancreatitis without cholangitis: a meta-analysis of randomized trials.

Authors:  Maxim S Petrov; Hjalmar C van Santvoort; Marc G H Besselink; Geert J M G van der Heijden; Karel J van Erpecum; Hein G Gooszen
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9.  Management guidelines for gallstone pancreatitis. Are the targets achievable?

Authors:  Pandanaboyana Sanjay; Sim Yeeting; Carole Whigham; Hannah K Judson; Christoph Kulli; Francesco M Polignano; Iain S Tait
Journal:  JOP       Date:  2009-01-08

10.  Diagnostic assessment and outcome of acute pancreatitis in Italy: results of a prospective multicentre study. ProInf-AISP: Progetto informatizzato pancreatite acuta, Associazione Italiana Studio Pancreas, phase II.

Authors:  G Uomo; R Pezzilli; A Gabbrielli; L Castoldi; A Zerbi; L Frulloni; P De Rai; G Cavallini; V Di Carlo
Journal:  Dig Liver Dis       Date:  2007-07-10       Impact factor: 4.088

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Review 1.  Role and timing of endoscopy in acute biliary pancreatitis.

Authors:  Andrea Anderloni; Alessandro Repici
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2.  TLR4 Asp299Gly and Thr399Ile and TLR2 intron 2 microsatellite gene polymorphism in patients with acute biliary pancreatitis: Does it cause the disease?

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3.  Early endoscopic ultrasonography in acute biliary pancreatitis: A prospective pilot study.

Authors:  Andrea Anderloni; Marianna Galeazzi; Marco Ballarè; Michela Pagliarulo; Marco Orsello; Mario Del Piano; Alessandro Repici
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4.  IL-8 gene polymorphism in acute biliary and non biliary pancreatitis: probable cause of high level parameters?

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Journal:  Ann Hepatobiliary Pancreat Surg       Date:  2017-02-28

5.  Practice Patterns and Use of Endoscopic Retrograde Cholangiopancreatography in the Management of Recurrent Acute Pancreatitis.

Authors:  Jonathan B Reichstein; Vaishali Patel; Parit Mekaroonkamol; Sunil Dacha; Steven A Keilin; Qiang Cai; Field F Willingham
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  5 in total

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