Literature DB >> 21159810

Clinical challenges in the implementation of a tomotherapy service for head and neck cancer patients in a regional UK radiotherapy centre.

S Chatterjee1, J H Mott, G Smyth, S Dickson, W Dobrowsky, C G Kelly.   

Abstract

OBJECTIVE: Intensity-modulated radiotherapy (IMRT) is increasingly being used to treat head and neck cancer cases.
METHODS: We discuss the clinical challenges associated with the setting up of an image guided intensity modulated radiotherapy service for a subset of head and neck cancer patients, using a recently commissioned helical tomotherapy (HT) Hi Art (Tomotherapy Inc, WI) machine in this article. We also discuss the clinical aspects of the tomotherapy planning process, treatment and image guidance experiences for the first 10 head and neck cancer cases. The concepts of geographical miss along with tomotherapy-specific effects, including that of field width and megavoltage CT (MVCT) imaging strategy, have been highlighted using the first 10 head and neck cases treated.
RESULTS: There is a need for effective streamlining of all aspects of the service to ensure compliance with cancer waiting time targets. We discuss how patient toxicity audits are crucial to guide refinement of the newly set-up planning dose constraints.
CONCLUSION: This article highlights the important clinical issues one must consider when setting up a head and neck IMRT, image-guided radiotherapy service. It shares some of the clinical challenges we have faced during the setting up of a tomotherapy service. Implementation of a clinical tomotherapy service requires a multidisciplinary team approach and relies heavily on good team working and effective communication between different staff groups.

Entities:  

Mesh:

Year:  2010        PMID: 21159810      PMCID: PMC3473475          DOI: 10.1259/bjr/19586137

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  32 in total

1.  Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.

Authors:  Jacques Bernier; Christian Domenge; Mahmut Ozsahin; Katarzyna Matuszewska; Jean-Louis Lefèbvre; Richard H Greiner; Jordi Giralt; Philippe Maingon; Frédéric Rolland; Michel Bolla; Francesco Cognetti; Jean Bourhis; Anne Kirkpatrick; Martine van Glabbeke
Journal:  N Engl J Med       Date:  2004-05-06       Impact factor: 91.245

2.  The helical tomotherapy thread effect.

Authors:  M W Kissick; J Fenwick; J A James; R Jeraj; J M Kapatoes; H Keller; T R Mackie; G Olivera; E T Soisson
Journal:  Med Phys       Date:  2005-05       Impact factor: 4.071

Review 3.  History of tomotherapy.

Authors:  T R Mackie
Journal:  Phys Med Biol       Date:  2006-06-20       Impact factor: 3.609

4.  Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck.

Authors:  Vincent Grégoire; Avraham Eisbruch; Marc Hamoir; Peter Levendag
Journal:  Radiother Oncol       Date:  2006-04-17       Impact factor: 6.280

5.  Importance of patient examination to clinical quality assurance in head and neck radiation oncology.

Authors:  David I Rosenthal; Joshua A Asper; Jerry L Barker; Adam S Garden; K S Clifford Chao; William H Morrison; Randal S Weber; K Kian Ang
Journal:  Head Neck       Date:  2006-11       Impact factor: 3.147

Review 6.  Intensity-modulated radiation therapy in head and neck cancers: an update.

Authors:  Nancy Lee; Dev R Puri; Angel I Blanco; K S Clifford Chao
Journal:  Head Neck       Date:  2007-04       Impact factor: 3.147

7.  Comparison of linac based fractionated stereotactic radiotherapy and tomotherapy treatment plans for skull-base tumors.

Authors:  Emilie T Soisson; Wolfgang A Tomé; Gregory M Richards; Minesh P Mehta
Journal:  Radiother Oncol       Date:  2006-02-20       Impact factor: 6.280

8.  A phase I study of dose-escalated chemoradiation with accelerated intensity modulated radiotherapy in locally advanced head and neck cancer.

Authors:  Teresa Guerrero Urbano; Catharine H Clark; Vibeke N Hansen; Elizabeth J Adams; Roger A'Hern; Elizabeth A Miles; Helen McNair; Margaret Bidmead; Alan P Warrington; David P Dearnaley; Kevin J Harrington; Christopher M Nutting
Journal:  Radiother Oncol       Date:  2007-08-20       Impact factor: 6.280

9.  Intensity modulated radiotherapy improves target coverage and parotid gland sparing when delivering total mucosal irradiation in patients with squamous cell carcinoma of head and neck of unknown primary site.

Authors:  Shreerang Bhide; Catherine Clark; Kevin Harrington; Christopher M Nutting
Journal:  Med Dosim       Date:  2007       Impact factor: 1.482

10.  The potential for dose dumping in normal tissues with IMRT for pelvic and H&N cancers.

Authors:  Nandanuri M S Reddy; Andrzej K Mazur; Seshadri Sampath; Adrian Osian; Brij M Sood; Akkamma Ravi; Dattatreyudu Nori
Journal:  Med Dosim       Date:  2008       Impact factor: 1.482

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  5 in total

1.  Dosimetric and radiobiological comparison of helical tomotherapy, forward-planned intensity-modulated radiotherapy and two-phase conformal plans for radical radiotherapy treatment of head and neck squamous cell carcinomas.

Authors:  S Chatterjee; N Willis; S M Locks; J H Mott; C G Kelly
Journal:  Br J Radiol       Date:  2011-12       Impact factor: 3.039

2.  Validation of an updated evidence-based protocol for proactive gastrostomy tube insertion in patients with head and neck cancer.

Authors:  T E Brown; V Getliffe; M D Banks; B G M Hughes; C Y Lin; L M Kenny; J D Bauer
Journal:  Eur J Clin Nutr       Date:  2016-02-10       Impact factor: 4.016

3.  The value of image-guided intensity-modulated radiotherapy in challenging clinical settings.

Authors:  S J Treece; M Mukesh; Y L Rimmer; S J Tudor; J C Dean; R J Benson; D L Gregory; G Horan; S J Jefferies; S G Russell; M V Williams; C B Wilson; N G Burnet
Journal:  Br J Radiol       Date:  2013-01       Impact factor: 3.039

4.  New radiotherapy techniques do not reduce the need for nutrition intervention in patients with head and neck cancer.

Authors:  T Brown; M Banks; B G M Hughes; C Lin; L M Kenny; J D Bauer
Journal:  Eur J Clin Nutr       Date:  2015-08-26       Impact factor: 4.016

5.  Setup errors in patients with head-neck cancer (HNC), treated using the Intensity Modulated Radiation Therapy (IMRT) technique: how it influences the customised immobilisation systems, patient's pain and anxiety.

Authors:  Massimiliano Contesini; Monica Guberti; Roberta Saccani; Luca Braglia; Cinzia Iotti; Andrea Botti; Emilio Abbati; Marina Iemmi
Journal:  Radiat Oncol       Date:  2017-04-27       Impact factor: 3.481

  5 in total

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