Literature DB >> 21146977

Labour analgesia and the baby: good news is no news.

Felicity Reynolds1.   

Abstract

When investigating different methods of maternal pain relief in labour, neonatal outcome has not always been at the forefront, or else maternal changes, such as haemodynamics, fever, length of labour, need for oxytocin or type of delivery, are taken as surrogates for neonatal outcome. It is essential to examine the actual baby and to appreciate that labour pain itself has adverse consequences for the baby. For systemic analgesia, pethidine has been most extensively studied and compared with neuraxial analgesia. It depresses fetal muscular activity, aortic blood flow, short-term heart rate variability and oxygen saturation. In the newborn it exacerbates acidosis, depresses Apgar scores, respiration, neurobehavioural score, muscle tone and suckling. Alternatives have few advantages, remifentanil being the most promising. Neuraxial analgesia is associated with better Apgar scores and variable neurobehavioural changes. Neonatal acid-base status is not only better with epidural than with systemic opioid analgesia, it is also better than with no analgesia. The effect on breast feeding has yet to be established, though it is certainly no worse than that of systemic opioid analgesia. Variations in neuraxial technique have little impact on the newborn. Widespread ignorance of the benefit to the newborn of neuraxial labour analgesia in the UK among non-anaesthetists needs to be combated. Copyright Â
© 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 21146977     DOI: 10.1016/j.ijoa.2010.08.004

Source DB:  PubMed          Journal:  Int J Obstet Anesth        ISSN: 0959-289X            Impact factor:   2.603


  15 in total

Review 1.  Patient-controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour.

Authors:  Stephanie Weibel; Yvonne Jelting; Arash Afshari; Nathan Leon Pace; Leopold Hj Eberhart; Johanna Jokinen; Thorsten Artmann; Peter Kranke
Journal:  Cochrane Database Syst Rev       Date:  2017-04-13

Review 2.  [Analgesic drugs during pregnancy].

Authors:  S Hultzsch; C Schaefer
Journal:  Schmerz       Date:  2016-12       Impact factor: 1.107

3.  Maternal hemodynamics and computerized cardiotocography during labor with epidural analgesia.

Authors:  Stefano Raffaele Giannubilo; Mirco Amici; Simone Pizzi; Alessandro Simonini; Andrea Ciavattini
Journal:  Arch Gynecol Obstet       Date:  2022-06-15       Impact factor: 2.344

4.  Early-life factors affect risk of pain and fever in infants during teething periods.

Authors:  Carolina Un Lam; Chin-Ying Stephen Hsu; Robert Yee; David Koh; Yung Seng Lee; Mary Foong-Fong Chong; Meijin Cai; Kenneth Kwek; Seang Mei Saw; Peter Gluckman; Yap Seng Chong
Journal:  Clin Oral Investig       Date:  2015-11-23       Impact factor: 3.573

5.  Effects of epidural analgesia on labor length, instrumental delivery, and neonatal short-term outcome.

Authors:  Junichi Hasegawa; Antonio Farina; Giovanni Turchi; Yuko Hasegawa; Margherita Zanello; Simonetta Baroncini
Journal:  J Anesth       Date:  2012-09-11       Impact factor: 2.078

6.  Efficacy and Effects of Parenteral Pethidine or Meptazinol and Regional Analgesia for Pain Relief during Delivery. A Comparative Observational Study.

Authors:  J Singer; A Jank; S Amara; P D H Stepan; U Kaisers; C Hoehne
Journal:  Geburtshilfe Frauenheilkd       Date:  2016-09       Impact factor: 2.915

Review 7.  Pain management for women in labour: an overview of systematic reviews.

Authors:  Leanne Jones; Mohammad Othman; Therese Dowswell; Zarko Alfirevic; Simon Gates; Mary Newburn; Susan Jordan; Tina Lavender; James P Neilson
Journal:  Cochrane Database Syst Rev       Date:  2012-03-14

8.  Epidural analgesia, neonatal care and breastfeeding.

Authors:  Antonio Alberto Zuppa; Giovanni Alighieri; Riccardo Riccardi; Maria Cavani; Alma Iafisco; Francesco Cota; Costantino Romagnoli
Journal:  Ital J Pediatr       Date:  2014-11-29       Impact factor: 2.638

Review 9.  Regional anesthesia in patients with pregnancy induced hypertension.

Authors:  Saravanan P Ankichetty; Ki Jinn Chin; Vincent W Chan; Raj Sahajanandan; Hungling Tan; Anju Grewal; Anahi Perlas
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2013-10

10.  Effects of maternal epidural analgesia on the neonate--a prospective cohort study.

Authors:  Bikash Shrestha; Amit Devgan; Mukti Sharma
Journal:  Ital J Pediatr       Date:  2014-12-10       Impact factor: 2.638

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