Literature DB >> 21145496

"TORCing" neutrophil chemotaxis.

Pascale G Charest1, Richard A Firtel.   

Abstract

During cell migration, chemoattractant-induced signaling pathways determine the direction of movement by controlling the spatiotemporal dynamics of cytoskeletal components. In this issue of Developmental Cell, Liu et al. report that the target of rapamycin complex 2 (TORC2) controls cell polarity and chemotaxis through regulation of both F-actin and myosin II in migrating neutrophils.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 21145496      PMCID： PMC3033560          DOI： 10.1016/j.devcel.2010.11.017

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  8 in total

1.  Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis.

Authors:  Kersi N Pestonjamasp; Carol Forster; Chunxiang Sun; Elisabeth M Gardiner; Ben Bohl; Orion Weiner; Gary M Bokoch; Michael Glogauer
Journal:  Blood       Date:  2006-06-29       Impact factor: 22.113

2.  A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils.

Authors:  Dana C Mahadeo; Mirkka Janka-Junttila; Rory L Smoot; Pavla Roselova; Carole A Parent
Journal:  Mol Biol Cell       Date:  2006-11-29       Impact factor: 4.138

Review 3.  TOR complex 2: a signaling pathway of its own.

Authors:  Nadine Cybulski; Michael N Hall
Journal:  Trends Biochem Sci       Date:  2009-10-28       Impact factor: 13.807

4.  A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration.

Authors:  Pascale G Charest; Zhouxin Shen; Ashley Lakoduk; Atsuo T Sasaki; Steven P Briggs; Richard A Firtel
Journal:  Dev Cell       Date:  2010-05-18       Impact factor: 12.270

5.  TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

Authors:  Susan Lee; Frank I Comer; Atsuo Sasaki; Ian X McLeod; Yung Duong; Koichi Okumura; John R Yates; Carole A Parent; Richard A Firtel
Journal:  Mol Biol Cell       Date:  2005-08-03       Impact factor: 4.138

6.  Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis.

Authors:  Huaqing Cai; Satarupa Das; Yoichiro Kamimura; Yu Long; Carole A Parent; Peter N Devreotes
Journal:  J Cell Biol       Date:  2010-07-26       Impact factor: 10.539

Review 7.  The signaling mechanisms underlying cell polarity and chemotaxis.

Authors:  Fei Wang
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-10       Impact factor: 10.005

8.  PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Authors:  Yoichiro Kamimura; Yuan Xiong; Pablo A Iglesias; Oliver Hoeller; Parvin Bolourani; Peter N Devreotes
Journal:  Curr Biol       Date:  2008-07-22       Impact factor: 10.834
  8 in total
  4 in total

Review 1.  Signaling mechanisms for chemotaxis.

Authors:  Yu Wang; Chun-Lin Chen; Miho Iijima
Journal:  Dev Growth Differ       Date:  2011-05       Impact factor: 2.053

2.  Mast cell chemotaxis - chemoattractants and signaling pathways.

Authors:  Ivana Halova; Lubica Draberova; Petr Draber
Journal:  Front Immunol       Date:  2012-05-25       Impact factor: 7.561

3.  De- and repolarization mechanism of flagellar morphogenesis during a bacterial cell cycle.

Authors:  Nicole J Davis; Yaniv Cohen; Stefano Sanselicio; Coralie Fumeaux; Shogo Ozaki; Jennifer Luciano; Ricardo C Guerrero-Ferreira; Elizabeth R Wright; Urs Jenal; Patrick H Viollier
Journal:  Genes Dev       Date:  2013-09-15       Impact factor: 11.361

4.  Proteomic and Transcriptomic Profiling Identifies Early Developmentally Regulated Proteins in Dictyostelium Discoideum.

Authors:  Óscar González-Velasco; Javier De Las Rivas; Jesus Lacal
Journal:  Cells       Date:  2019-10-01       Impact factor: 6.600
  4 in total

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