Literature DB >> 21585354

Signaling mechanisms for chemotaxis.

Yu Wang1, Chun-Lin Chen, Miho Iijima.   

Abstract

Cells recognize external chemical gradients and translate these environmental cues into amplified intracellular signaling that results in elongated cell shape, actin polymerization toward the leading edge, and movement along the gradient. Mechanisms underlying chemotaxis are conserved evolutionarily from Dictyostelium amoeba to mammalian neutrophils. Recent studies have uncovered several parallel intracellular signaling pathways that crosstalk in chemotaxing cells. Here, we review these signaling mechanisms in Dictyostelium discoideum.
© 2011 The Authors. Development, Growth & Differentiation © 2011 Japanese Society of Developmental Biologists.

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Year:  2011        PMID： 21585354      PMCID： PMC3098469          DOI： 10.1111/j.1440-169X.2011.01265.x

Source DB:  PubMed          Journal:  Dev Growth Differ        ISSN： 0012-1592            Impact factor:   2.053


  87 in total

1.  Localization of the G protein betagamma complex in living cells during chemotaxis.

Authors:  T Jin; N Zhang; Y Long; C A Parent; P N Devreotes
Journal:  Science       Date:  2000-02-11       Impact factor: 47.728

Review 2.  Chemotaxis: signalling the way forward.

Authors:  Peter J M Van Haastert; Peter N Devreotes
Journal:  Nat Rev Mol Cell Biol       Date:  2004-08       Impact factor: 94.444

3.  RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.

Authors:  Leonard Bosgraaf; Arjen Waijer; Ruchira Engel; Antonie J W G Visser; Deborah Wessels; David Soll; Peter J M van Haastert
Journal:  J Cell Sci       Date:  2005-04-12       Impact factor: 5.285

4.  RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation.

Authors:  C J Lim; G B Spiegelman; G Weeks
Journal:  EMBO J       Date:  2001-08-15       Impact factor: 11.598

Review 5.  Highlighting the role of Ras and Rap during Dictyostelium chemotaxis.

Authors:  Arjan Kortholt; Peter J M van Haastert
Journal:  Cell Signal       Date:  2008-04-01       Impact factor: 4.315

6.  Arachidonic acid is a chemoattractant for Dictyostelium discoideum cells.

Authors:  Ralph H Schaloske; Dagmar Blaesius; Christina Schlatterer; Daniel F Lusche
Journal:  J Biosci       Date:  2007-12       Impact factor: 1.826

Review 7.  Signaling through chemoattractant receptors in Dictyostelium.

Authors:  M Y Chen; R H Insall; P N Devreotes
Journal:  Trends Genet       Date:  1996-02       Impact factor: 11.639

8.  Two cAMP receptors activate common signaling pathways in Dictyostelium.

Authors:  R H Insall; R D Soede; P Schaap; P N Devreotes
Journal:  Mol Biol Cell       Date:  1994-06       Impact factor: 4.138

9.  PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Authors:  Yoichiro Kamimura; Yuan Xiong; Pablo A Iglesias; Oliver Hoeller; Parvin Bolourani; Peter N Devreotes
Journal:  Curr Biol       Date:  2008-07-22       Impact factor: 10.834

10.  CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.

Authors:  R Insall; A Kuspa; P J Lilly; G Shaulsky; L R Levin; W F Loomis; P Devreotes
Journal:  J Cell Biol       Date:  1994-09       Impact factor: 10.539
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  29 in total

1.  Myosin I links PIP3 signaling to remodeling of the actin cytoskeleton in chemotaxis.

Authors:  Chun-Lin Chen; Yu Wang; Hiromi Sesaki; Miho Iijima
Journal:  Sci Signal       Date:  2012-01-31       Impact factor: 8.192

2.  Rho GTPases orient directional sensing in chemotaxis.

Authors:  Yu Wang; Hiroshi Senoo; Hiromi Sesaki; Miho Iijima
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-18       Impact factor: 11.205

3.  A GPCR Handles Bacterial Sensing in Chemotaxis and Phagocytosis.

Authors:  Hiroshi Senoo; Hiromi Sesaki; Miho Iijima
Journal:  Dev Cell       Date:  2016-02-22       Impact factor: 12.270

4.  Rho GTPase: A molecular compass for directional cell migration.

Authors:  Hiroshi Senoo; Miho Iijima
Journal:  Commun Integr Biol       Date:  2014-01-08

Review 5.  The role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migration.

Authors:  C-Y Wu; M-W Lin; D-C Wu; Y-B Huang; H-T Huang; C-L Chen
Journal:  Br J Pharmacol       Date:  2014-11-24       Impact factor: 8.739

6.  The IplA Ca2+ channel of Dictyostelium discoideum is necessary for chemotaxis mediated through Ca2+, but not through cAMP, and has a fundamental role in natural aggregation.

Authors:  Daniel F Lusche; Deborah Wessels; Amanda Scherer; Karla Daniels; Spencer Kuhl; David R Soll
Journal:  J Cell Sci       Date:  2012-02-28       Impact factor: 5.285

7.  Myosin heavy chain kinases play essential roles in Ca2+, but not cAMP, chemotaxis and the natural aggregation of Dictyostelium discoideum.

Authors:  Deborah Wessels; Daniel F Lusche; Paul A Steimle; Amanda Scherer; Spencer Kuhl; Kristen Wood; Brett Hanson; Thomas T Egelhoff; David R Soll
Journal:  J Cell Sci       Date:  2012-08-16       Impact factor: 5.285

8.  Role of methamphetamine on glioblastoma cytotoxicity induced by doxorubicin and methotrexate.

Authors:  Tânia Capelôa; Francisco Caramelo; Carlos Fontes-Ribeiro; Célia Gomes; Ana P Silva
Journal:  Neurotox Res       Date:  2014-03-21       Impact factor: 3.911

9.  Dipeptidyl peptidase IV is a human and murine neutrophil chemorepellent.

Authors:  Sarah E Herlihy; Darrell Pilling; Anu S Maharjan; Richard H Gomer
Journal:  J Immunol       Date:  2013-05-15       Impact factor: 5.422

10.  Protease activated-receptor 2 is necessary for neutrophil chemorepulsion induced by trypsin, tryptase, or dipeptidyl peptidase IV.

Authors:  Michael J V White; Luis E Chinea; Darrell Pilling; Richard H Gomer
Journal:  J Leukoc Biol       Date:  2017-12-11       Impact factor: 4.962
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