OBJECTIVES: This study tested the effectiveness of a smoking cessation program designed for patients with peripheral artery disease (PAD). BACKGROUND: Tobacco use is the leading risk factor for PAD incidence and progression and for ischemic events. Tobacco cessation reduces PAD-related morbidity and mortality, yet few prospective clinical trials have evaluated smoking cessation interventions in PAD patients. METHODS: We recruited outpatients with lower extremity PAD identified from medical records as cigarette smokers. Participants were randomly assigned to an intensive tailored PAD-specific counseling intervention or a minimal intervention. Participants completed surveys at baseline and at 3- and 6-month follow-up. Reported 7-day point prevalent smoking abstinence was confirmed by cotinine or carbon monoxide assessment. RESULTS: In all, 687 outpatients were identified as probable smokers with lower extremity PAD; 232 met study eligibility requirements; and 124 (53% of eligible) enrolled. Participants were receptive to counselor contact: the median number of sessions was 8.5 (range 0 to 18). Participants randomly assigned to the intensive intervention group were significantly more likely to be confirmed abstinent at 6-month follow-up: 21.3% versus 6.8% in the minimal intervention group (chi-square = 5.21, p = 0.023). CONCLUSIONS: Many long-term smokers with PAD are willing to initiate a serious quit attempt and to engage in an intensive smoking cessation program. Intensive intervention for tobacco dependence is a more effective smoking cessation intervention than minimal care. Studies should be conducted to examine the long-term effectiveness of intensive smoking cessation programs in this population to examine the effect of this intervention on clinical outcomes related to PAD.
RCT Entities:
OBJECTIVES: This study tested the effectiveness of a smoking cessation program designed for patients with peripheral artery disease (PAD). BACKGROUND:Tobacco use is the leading risk factor for PAD incidence and progression and for ischemic events. Tobacco cessation reduces PAD-related morbidity and mortality, yet few prospective clinical trials have evaluated smoking cessation interventions in PAD patients. METHODS: We recruited outpatients with lower extremity PAD identified from medical records as cigarette smokers. Participants were randomly assigned to an intensive tailored PAD-specific counseling intervention or a minimal intervention. Participants completed surveys at baseline and at 3- and 6-month follow-up. Reported 7-day point prevalent smoking abstinence was confirmed by cotinine or carbon monoxide assessment. RESULTS: In all, 687 outpatients were identified as probable smokers with lower extremity PAD; 232 met study eligibility requirements; and 124 (53% of eligible) enrolled. Participants were receptive to counselor contact: the median number of sessions was 8.5 (range 0 to 18). Participants randomly assigned to the intensive intervention group were significantly more likely to be confirmed abstinent at 6-month follow-up: 21.3% versus 6.8% in the minimal intervention group (chi-square = 5.21, p = 0.023). CONCLUSIONS: Many long-term smokers with PAD are willing to initiate a serious quit attempt and to engage in an intensive smoking cessation program. Intensive intervention for tobacco dependence is a more effective smoking cessation intervention than minimal care. Studies should be conducted to examine the long-term effectiveness of intensive smoking cessation programs in this population to examine the effect of this intervention on clinical outcomes related to PAD.
Authors: Joseph T Ciccolo; David M Williams; Shira I Dunsiger; James W Whitworth; Aston K McCullough; Beth B Bock; Bess H Marcus; Merle Myerson Journal: Ment Health Phys Act Date: 2014-06-01
Authors: Marie D Gerhard-Herman; Heather L Gornik; Coletta Barrett; Neal R Barshes; Matthew A Corriere; Douglas E Drachman; Lee A Fleisher; Francis Gerry R Fowkes; Naomi M Hamburg; Scott Kinlay; Robert Lookstein; Sanjay Misra; Leila Mureebe; Jeffrey W Olin; Rajan A G Patel; Judith G Regensteiner; Andres Schanzer; Mehdi H Shishehbor; Kerry J Stewart; Diane Treat-Jacobson; M Eileen Walsh Journal: Circulation Date: 2016-11-13 Impact factor: 29.690
Authors: W Michael Hooten; Cynthia O Townsend; J Taylor Hays; Kaye L Ebnet; Thomas R Gauvin; Jessica M Gehin; Heidi J Laures; Christi A Patten; David O Warner Journal: Addict Behav Date: 2013-11-21 Impact factor: 3.913
Authors: Damianos G Kokkinidis; Stefanos Giannopoulos; Moosa Haider; Timothy Jordan; Anita Sarkar; Gagan D Singh; Eric A Secemsky; Jay Giri; Joshua A Beckman; Ehrin J Armstrong Journal: Vasc Med Date: 2020-05-27 Impact factor: 3.239
Authors: Karina Newhall; Mary Burnette; Benjamin S Brooke; Andres Schanzer; TzeWoei Tan; Susan Flocke; Alik Farber; Philip Goodney Journal: J Vasc Surg Date: 2015-12-30 Impact factor: 4.268
Authors: Andrew W Hoel; Brian W Nolan; Philip P Goodney; Yuanyuan Zhao; Andres Schanzer; Andrew C Stanley; Jens Eldrup-Jorgensen; Jack L Cronenwett Journal: J Vasc Surg Date: 2013-01-30 Impact factor: 4.268