| Literature DB >> 21142861 |
Myrthala Moreno-Smith1, Susan K Lutgendorf, Anil K Sood.
Abstract
The influence of psychosocial factors on the development and progression of cancer has been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical studies over the past 30 years have provided strong evidence for links between chronic stress, depression and social isolation and cancer progression. By contrast, there is only limited evidence for the role of these behavioral factors in cancer initiation. Recent cellular and molecular studies have identified specific signaling pathways that impact cancer growth and metastasis. This article provides an overview of the relationship between psychosocial factors, specifically chronic stress, and cancer progression.Entities:
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Year: 2010 PMID: 21142861 PMCID: PMC3037818 DOI: 10.2217/fon.10.142
Source DB: PubMed Journal: Future Oncol ISSN: 1479-6694 Impact factor: 3.404