Literature DB >> 21142861

Impact of stress on cancer metastasis.

Myrthala Moreno-Smith1, Susan K Lutgendorf, Anil K Sood.   

Abstract

The influence of psychosocial factors on the development and progression of cancer has been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical studies over the past 30 years have provided strong evidence for links between chronic stress, depression and social isolation and cancer progression. By contrast, there is only limited evidence for the role of these behavioral factors in cancer initiation. Recent cellular and molecular studies have identified specific signaling pathways that impact cancer growth and metastasis. This article provides an overview of the relationship between psychosocial factors, specifically chronic stress, and cancer progression.

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Year:  2010        PMID: 21142861      PMCID: PMC3037818          DOI: 10.2217/fon.10.142

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.404


  253 in total

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  148 in total

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