Literature DB >> 21132122

Challenges and opportunities in dermal/transdermal delivery.

Kalpana S Paudel1, Mikolaj Milewski, Courtney L Swadley, Nicole K Brogden, Priyanka Ghosh, Audra L Stinchcomb.   

Abstract

Transdermal drug delivery is an exciting and challenging area. There are numerous transdermal delivery systems currently available on the market. However, the transdermal market still remains limited to a narrow range of drugs. Further advances in transdermal delivery depend on the ability to overcome the challenges faced regarding the permeation and skin irritation of the drug molecules. Emergence of novel techniques for skin permeation enhancement and development of methods to lessen skin irritation would widen the transdermal market for hydrophilic compounds, macromolecules and conventional drugs for new therapeutic indications. As evident from the ongoing clinical trials of a wide variety of drugs for various clinical conditions, there is a great future for transdermal delivery of drugs.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21132122      PMCID： PMC2995530          DOI： 10.4155/tde.10.16

Source DB:  PubMed          Journal:  Ther Deliv        ISSN： 2041-5990


  101 in total

1.  Transdermal drug delivery by jet injectors: energetics of jet formation and penetration.

Authors:  Joy Schramm; Samir Mitragotri
Journal:  Pharm Res       Date:  2002-11       Impact factor: 4.200

2.  Coated microneedles for transdermal delivery.

Authors:  Harvinder S Gill; Mark R Prausnitz
Journal:  J Control Release       Date:  2006-10-24       Impact factor: 9.776

Review 3.  Nanotechnology and the transdermal route: A state of the art review and critical appraisal.

Authors:  Gregor Cevc; Ulrich Vierl
Journal:  J Control Release       Date:  2009-10-20       Impact factor: 9.776

4.  Effect of coadministration of corticosteroids on the development of contact sensitization.

Authors:  A A Amkraut; W P Jordan; L Taskovich
Journal:  J Am Acad Dermatol       Date:  1996-07       Impact factor: 11.527

5.  Predictive testing of metalworking fluids: a comparison of 2 cumulative human irritation models and correlation with epidemiological data.

Authors:  W Wigger-Alberti; U Hinnen; P Elsner
Journal:  Contact Dermatitis       Date:  1997-01       Impact factor: 6.600

Review 6.  Electrically-assisted transdermal drug delivery.

Authors:  J E Riviere; M C Heit
Journal:  Pharm Res       Date:  1997-06       Impact factor: 4.200

7.  Physicochemical considerations in the iontophoretic delivery of a small peptide: in vitro studies using arginine vasopressin as a model peptide.

Authors:  Vinod Nair; Ramesh Panchagnula
Journal:  Pharmacol Res       Date:  2003-08       Impact factor: 7.658

8.  Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation.

Authors:  J-Y Fang; W-R Lee; S-C Shen; Y-P Fang; C-H Hu
Journal:  Br J Dermatol       Date:  2004-07       Impact factor: 9.302

9.  Flux across [corrected] microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro.

Authors:  Stan L Banks; Raghotham R Pinninti; Harvinder S Gill; Peter A Crooks; Mark R Prausnitz; Audra L Stinchcomb
Journal:  Pharm Res       Date:  2008-05-01       Impact factor: 4.200

10.  Selective removal of stratum corneum by microdermabrasion to increase skin permeability.

Authors:  Harvinder S Gill; Samantha N Andrews; Senthilkumar K Sakthivel; Andrew Fedanov; Ifor R Williams; David A Garber; Frances H Priddy; Seth Yellin; Mark B Feinberg; Silvija I Staprans; Mark R Prausnitz
Journal:  Eur J Pharm Sci       Date:  2009-06-25       Impact factor: 4.384
View more
  76 in total

1.  Effect of local controlled heat on transdermal delivery of nicotine.

Authors:  Kristian Kjær Petersen; Mark Lillelund Rousing; Carina Jensen; Lars Arendt-Nielsen; Parisa Gazerani
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2011-09-08

2.  In Vitro and In Vivo Performance of a Pre-Filled, Electrochemically-Actuated Infusion System.

Authors:  Assaf Shaked; Ella Tenenbaum-Koren; Jacob Atsmon; Peter Noymer
Journal:  Pharm Res       Date:  2015-07-29       Impact factor: 4.200

3.  Diclofenac Loaded Lipid Nanovesicles Prepared by Double Solvent Displacement for Skin Drug Delivery.

Authors:  M Sala; F Locher; M Bonvallet; G Agusti; A Elaissari; H Fessi
Journal:  Pharm Res       Date:  2017-06-19       Impact factor: 4.200

Review 4.  Microneedle characterisation: the need for universal acceptance criteria and GMP specifications when moving towards commercialisation.

Authors:  Rebecca E M Lutton; Jessica Moore; Eneko Larrañeta; Stephen Ligett; A David Woolfson; Ryan F Donnelly
Journal:  Drug Deliv Transl Res       Date:  2015-08       Impact factor: 4.617

5.  A miniature, single use, skin-adhered, low-voltage, electroosmotic pumping-based subcutaneous infusion system.

Authors:  Woonsup Shin; Samuel Jaeho Shin; Jong Myung Lee; Rajaram Krishna Nagarale; Adam Heller
Journal:  Drug Deliv Transl Res       Date:  2011-08       Impact factor: 4.617

6.  Non-invasive Oil-Based Method to Increase Topical Delivery of Nucleic Acids to Skin.

Authors:  Manika Vij; Shamshad Alam; Nidhi Gupta; Vishvabandhu Gotherwal; Hemlata Gautam; Kausar M Ansari; Deenan Santhiya; Vivek T Natarajan; Munia Ganguli
Journal:  Mol Ther       Date:  2017-03-30       Impact factor: 11.454

7.  Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.

Authors:  D C Hammell; L P Zhang; F Ma; S M Abshire; S L McIlwrath; A L Stinchcomb; K N Westlund
Journal:  Eur J Pain       Date:  2015-10-30       Impact factor: 3.931

Review 8.  Single compartment drug delivery.

Authors:  Michael J Cima; Heejin Lee; Karen Daniel; Laura M Tanenbaum; Aikaterini Mantzavinou; Kevin C Spencer; Qunya Ong; Jay C Sy; John Santini; Carl M Schoellhammer; Daniel Blankschtein; Robert S Langer
Journal:  J Control Release       Date:  2014-05-04       Impact factor: 9.776

9.  Laser facilitates week-long sustained transdermal drug delivery at high doses.

Authors:  Prateek Kakar; Zhuofan Li; Yibo Li; Yan Cao; Xinyuan Chen
Journal:  J Control Release       Date:  2020-01-07       Impact factor: 9.776

Review 10.  Polymeric nanoparticles-based topical delivery systems for the treatment of dermatological diseases.

Authors:  Zheng Zhang; Pei-Chin Tsai; Tannaz Ramezanli; Bozena B Michniak-Kohn
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2013-02-05
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.