Literature DB >> 21132096

The renin angiotensin system and the metabolic syndrome.

Chih-Hong Wang1, Feng Li, Nobuyuki Takahashi.   

Abstract

The renin angiotensin system (RAS) is important for fluid and blood pressure regulation. Recent studies suggest that an overactive RAS is involved in the metabolic syndrome. This article discusses recent advances on how genetic alteration of the RAS affects cardiovascular and metabolic phenotypes, with a special emphasis on the potential role of angiotensin-independent effects of renin.

Entities:  

Year:  2010        PMID： 21132096      PMCID： PMC2995894          DOI： 10.2174/1876526203010001

Source DB:  PubMed          Journal:  Open Hypertens J


  161 in total

Review 1.  Human genetics, animal models and computer simulations for studying hypertension.

Authors:  Nobuyuki Takahashi; Oliver Smithies
Journal:  Trends Genet       Date:  2004-03       Impact factor: 11.639

2.  Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysis.

Authors:  Eva Brand; Nathalie Chatelain; Françoise Paillard; Laurence Tiret; Sophie Visvikis; Mark Lathrop; Florent Soubrier; Florence Demenais
Journal:  Eur J Hum Genet       Date:  2002-11       Impact factor: 4.246

3.  Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse.

Authors:  W Huang; Y Gallois; N Bouby; P Bruneval; D Heudes; M F Belair; J H Krege; P Meneton; M Marre; O Smithies; F Alhenc-Gelas
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-30       Impact factor: 11.205

4.  Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

Authors:  Koichi Yamamoto; Mitsuru Ohishi; Tomohiro Katsuya; Norihisa Ito; Masashi Ikushima; Masaharu Kaibe; Yuji Tatara; Atsushi Shiota; Sumio Sugano; Satoshi Takeda; Hiromi Rakugi; Toshio Ogihara
Journal:  Hypertension       Date:  2006-02-27       Impact factor: 10.190

5.  The human B1 bradykinin receptor exhibits high ligand-independent, constitutive activity. Roles of residues in the fourth intracellular and third transmembrane domains.

Authors:  L M Leeb-Lundberg; D S Kang; M E Lamb; D B Fathy
Journal:  J Biol Chem       Date:  2000-12-27       Impact factor: 5.157

6.  Bradykinin B2 receptor gene C-58T polymorphism and insulin resistance. A study on obese patients.

Authors:  F Fallo; P Mulatero; R Vettor; A Scarda; P Della Mea; F Morello; F Veglio; T A Williams
Journal:  Horm Metab Res       Date:  2004-04       Impact factor: 2.936

Review 7.  eNOS, metabolic syndrome and cardiovascular disease.

Authors:  Paul L Huang
Journal:  Trends Endocrinol Metab       Date:  2009-07-31       Impact factor: 12.015

8.  Kinin B2 receptor is not involved in enalapril-induced apoptosis and regression of hypertrophy in spontaneously hypertensive rat aorta: possible role of B1 receptor.

Authors:  David Duguay; Shant Der Sarkissian; Rémi Kouz; Brice Ongali; Réjean Couture; Denis deBlois
Journal:  Br J Pharmacol       Date:  2004-01-26       Impact factor: 8.739

9.  Brain-specific restoration of angiotensin II corrects renal defects seen in angiotensinogen-deficient mice.

Authors:  Nadheige Lochard; David W Silversides; Jorge P van Kats; Chantal Mercure; Timothy L Reudelhuber
Journal:  J Biol Chem       Date:  2002-10-23       Impact factor: 5.157

10.  Role of kinin B1 and B2 receptors in a rat model of neuropathic pain.

Authors:  M Petcu; J P Dias; B Ongali; G Thibault; W Neugebauer; R Couture
Journal:  Int Immunopharmacol       Date:  2007-09-29       Impact factor: 4.932
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  12 in total

1.  High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats.

Authors:  Preethi Samuel; Quaisar Ali; Rifat Sabuhi; Yonnie Wu; Tahir Hussain
Journal:  Am J Physiol Renal Physiol       Date:  2012-05-16

2.  Pharmacologic effects of 2-methoxyestradiol on angiotensin type 1 receptor down-regulation in rat liver epithelial and aortic smooth muscle cells.

Authors:  Sivaramakrishna Koganti; Russell Snyder; Thomas Thekkumkara
Journal:  Gend Med       Date:  2012-02-25

3.  The gene knockout of angiotensin II type 1a receptor improves high-fat diet-induced obesity in rat via promoting adipose lipolysis.

Authors:  Aiyun Li; Wenjuan Shi; Jin Wang; Xuejiao Wang; Yan Zhang; Zhandong Lei; Xiang-Ying Jiao
Journal:  PLoS One       Date:  2022-07-08       Impact factor: 3.752

4.  The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II.

Authors:  Huixin Guo; Baoxin Liu; Lei Hou; Erlinda The; Gang Li; Dongzhi Wang; Qiqiang Jie; Wenliang Che; Yidong Wei
Journal:  Int J Mol Med       Date:  2015-03-02       Impact factor: 4.101

5.  Expression and clinical significance of angiotensin II type 1 receptor in human hepatocellular carcinoma.

Authors:  Yun-Fei Duan; Xiao-Dong Li; Feng Zhu; Feng Zhang
Journal:  Exp Ther Med       Date:  2013-11-15       Impact factor: 2.447

6.  Enhancement of Adipocyte Browning by Angiotensin II Type 1 Receptor Blockade.

Authors:  Kana Tsukuda; Masaki Mogi; Jun Iwanami; Harumi Kanno; Hirotomo Nakaoka; Xiao-Li Wang; Hui-Yu Bai; Bao-Shuai Shan; Masayoshi Kukida; Akinori Higaki; Toshifumi Yamauchi; Li-Juan Min; Masatsugu Horiuchi
Journal:  PLoS One       Date:  2016-12-19       Impact factor: 3.240

7.  Angiotensin AT(2) receptor contributes towards gender bias in weight gain.

Authors:  Preethi Samuel; Mohammad Azhar Khan; Sourashish Nag; Tadashi Inagami; Tahir Hussain
Journal:  PLoS One       Date:  2013-01-15       Impact factor: 3.240

8.  Comparison of the relationships of alcoholic and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia.

Authors:  Nobuyuki Toshikuni; Atsushi Fukumura; Nobuhiko Hayashi; Tomoe Nomura; Mutsumi Tsuchishima; Tomiyasu Arisawa; Mikihiro Tsutsumi
Journal:  J Clin Biochem Nutr       Date:  2012-11-13       Impact factor: 3.114

9.  Effects of Azilsartan, Aliskiren or their Combination on High Fat Diet-induced Non-alcoholic Liver Disease Model in Rats.

Authors:  Saad Abdulrahman Hussain; Rabab Mohammed Utba; Ajwad Muhammad Assumaidaee
Journal:  Med Arch       Date:  2017-08

10.  Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome.

Authors:  Nut Palachai; Jintanaporn Wattanathorn; Supaporn Muchimapura; Wipawee Thukham-Mee
Journal:  Oxid Med Cell Longev       Date:  2019-11-11       Impact factor: 6.543
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