| Literature DB >> 21132067 |
Shen Hu1,2, David T Wong3,4.
Abstract
Lectin microarray is a new technology that utilizes a panel of lectins immobilized on well-defined substrate for high-throughout analysis of glycans and glycoproteins. In this article, we have reviewed the fabrication and detection schemes in lectin microarray and discussed its novel applications in glycomics. We have also demonstrated a lectin array on PDMS with MALDI-TOF-MS for glycoprotein analysis. This method has been demonstrated for differential analysis of serum glycoproteins in oral cancer and healthy control subjects.Entities:
Keywords: Glycan; Lectin; Oral cancer; Protein microarray
Year: 2009 PMID: 21132067 PMCID: PMC2995448 DOI: 10.1002/prca.200800153
Source DB: PubMed Journal: Proteomics Clin Appl ISSN: 1862-8346 Impact factor: 3.494