Literature DB >> 21132029

A Comparative Dosimetric Study of Adjuvant 3D Conformal Radiotherapy for Operable Stomach Cancer Versus AP-PA Conventional Radiotherapy in NCI-Cairo.

Hesham A El-Hossiny1, Nashaat A Diab, Maha M El-Taher.   

Abstract

PURPOSE: This study was to compare this multiplefield conformal technique to the AP-PA technique with respect to target volume coverage and dose to normal tissues.
MATERIALS AND METHODS: Seventeen patients with stages II-III denocarcinoma of the stomach were treated with adjuvant postoperative chemoradiotherapy presented to radiotherapy department in National Cancer Institute, Cairo in period between February 2009 to March 2010 using 3D conformal radiotherapy technique that consisted of a monoisocentric arrangement employing 4-6 radiation fields. For each patient, a second radiotherapy treatment plan was done using an antroposterior (AP-PA) fields, the two techniques were then compared using dose volume histogram (DVH) analysis.
RESULTS: Comparing different DVHs, it was found that the planning target volume (PTV) was adequately covered in both (3D & 2D) plans while the left kidney and spinal cord demonstrate lower radiation doses on using the conformal technique. The liver doses is higher in the 3D tecq, but still well below liver tolerance.
CONCLUSIONS: Both 3D conformal radiotherapy and AP-PA conventional techniques doses are within range of normal tissues tolerance. Regarding the left kidney and spinal cord the 3D conformal radiotherapy is superior than the AP-PA conventional techniques but with higher doses to the liver in the 3D conformal radiotherapy compared to the AP-PA conventional techniques. KEY WORDS: Dosimetric study in cancer stomach.

Entities:  

Year:  2009        PMID: 21132029

Source DB:  PubMed          Journal:  J Egypt Natl Canc Inst        ISSN: 1110-0362


  6 in total

1.  Can we obtain planning goals for conformal techniques in neoadjuvant and adjuvant radiochemotherapy for gastric cancer patients?

Authors:  Wojciech Leszczyński; Paweł Polanowski; Paulina Leszczyńska; Leszek Hawrylewicz; Iwona Brąclik; Rafał Kawczyński; Jerzy Wydmański
Journal:  Rep Pract Oncol Radiother       Date:  2016-02-08

2.  Phase I study of postoperative radiotherapy concurrent with S-1 in patients with gastric cancer.

Authors:  Meng Qiu; Xing-chen Peng; Feng Bi; Xin Wang; Qiu Li; Feng Xu; Zhi-ping Li; Ya-li Shen; Ji-yan Liu; Ya-qing Zhao; Dan Cao; Hong-feng Gou; Yu Yang; Ye Chen; Cheng Yi
Journal:  Med Oncol       Date:  2015-05-30       Impact factor: 3.064

3.  A phase II trial of concurrent 3D-CRT/IMRT and oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX) in gastric cancer patients with R0 gastrectomy and D2 lymph node dissection.

Authors:  Xin Wang; Yali Shen; Hong Zhu; Yaqin Zhao; Zhiping Li; Meng Qiu; Qiu Li; Hongfeng Gou; Yu Yang; Dan Cao; Jiyan Liu; Cheng Yi; Zhengyin Liao; Deyun Luo; Feng Bi; Feng Xu
Journal:  Gastric Cancer       Date:  2015-01-22       Impact factor: 7.370

4.  To Optimize Radiotherapeutic Plans for Superior Tumor Coverage Predicts Malignant Glioma Prognosis and Normal Tissue Complication Probability.

Authors:  Chun-Yuan Kuo; Wei-Hsiu Liu; Yu-Ching Chou; Ming-Hsien Li; Jo-Ting Tsai; David Yc Huang; Jang-Chun Lin
Journal:  J Clin Med       Date:  2022-04-25       Impact factor: 4.964

Review 5.  Planning comparison between standard and conformal 3D techniques in post-operative radiotherapy of gastric cancer: a systematic review.

Authors:  A G Morganti; A Di Castelnuovo; M Massaccesi; F Cellini; S Cilla; G Macchia; P Forte; M Buwenge; C Digesu; M Ferro; V Picardi; L Caravatta; V Valentini; F Deodato
Journal:  Br J Radiol       Date:  2013-07-26       Impact factor: 3.039

6.  Dosimetric Comparison of Three Different Radiotherapy Techniques in Antrum-Located Stomach Cancer

Authors:  Alparslan Serarslan; Nilgun Ozbek Okumus; Bilge Gursel; Deniz Meydan; Yalcin Dastan; Talat Aksu
Journal:  Asian Pac J Cancer Prev       Date:  2017-03-01
  6 in total

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