Literature DB >> 21126706

Surgical therapy of gastro-oesophageal reflux disease.

Lars Lundell1.   

Abstract

Surgery should always be looked upon as complementary to medical therapy in the long-term management of patients with chronic GORD. Available medical therapies are effective and adequate for the control of disease manifestations in the great majority of GORD patients. For patients who have a suboptimal disease control under medical therapy and in those who for various reasons want to discuss an alternative to medical long-term therapy, the following message can be transmitted. Anti reflux surgery is a well-documented effective long-term therapeutic alternative to control GORD. The outcome after surgery is dependent on the experience and quality of the surgeon. These operations are safe but mortality can never attain a zero level and the morbidity has to be realised. Anti reflux surgery has to be centralised within each country. With the aim of optimising the outcome of anti reflux surgery, the surgeon has to perform and master a delicate act of balance on the choice between various fundoplication procedures. On one hand we have the total fundoplication with its proved efficacy regarding reflux control but with it associated somewhat more frequent mechanical side-effects. The posterior partial fundoplication has obvious advantages with less postfundoplication complaints without compromising the level of reflux control and can therefore often be recommended. Most studies present very promising results following anterior partial fundoplications. The spectrum of postfundoplication symptoms can be minimised provided that the surgeon fully comprehend the mechanism of action of these procedures and adhere to technical perfectionism. Evaluation and management of failures after anti reflux surgery have to be centralised within each country.
Copyright © 2010. Published by Elsevier Ltd.

Entities:  

Mesh:

Year:  2010        PMID: 21126706     DOI: 10.1016/j.bpg.2010.09.006

Source DB:  PubMed          Journal:  Best Pract Res Clin Gastroenterol        ISSN: 1521-6918            Impact factor:   3.043


  7 in total

1.  Antireflux surgery: efficacy, side effects, and other issues.

Authors:  Lars Lundell
Journal:  Gastroenterol Hepatol (N Y)       Date:  2011-03

Review 2.  Surgical treatment of gastroesophageal reflux disease.

Authors:  Christian A Gutschow; Arnulf H Hölscher
Journal:  Langenbecks Arch Surg       Date:  2012-04-12       Impact factor: 3.445

3.  New Approaches to Management of PPI-Refractory Gastroesophageal Reflux Disease.

Authors:  Fehmi Ates; Michael F Vaezi
Journal:  Curr Treat Options Gastroenterol       Date:  2014-03

4.  LATE EVALUATION OF PATIENTS OPERATED FOR GASTROESOPHAGEAL REFLUX DISEASE BY NISSEN FUNDOPLICATION.

Authors:  Maxwel Capsy Boga Ribeiro; Amanda Bueno de Araújo; Juverson Alves Terra-Júnior; Eduardo Crema; Nelson Adami Andreollo
Journal:  Arq Bras Cir Dig       Date:  2016 Jul-Sep

Review 5.  Economic evaluations of gastroesophageal reflux disease medical management.

Authors:  Andrew J Gawron; Dustin D French; John E Pandolfino; Colin W Howden
Journal:  Pharmacoeconomics       Date:  2014-08       Impact factor: 4.981

6.  Modern medical and surgical management of difficult-to-treat GORD.

Authors:  Frank Zerbib; Daniel Sifrim; Radu Tutuian; Stephen Attwood; Lars Lundell
Journal:  United European Gastroenterol J       Date:  2013-02       Impact factor: 4.623

Review 7.  Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression.

Authors:  Carmelo Scarpignato; Luigi Gatta; Angelo Zullo; Corrado Blandizzi
Journal:  BMC Med       Date:  2016-11-09       Impact factor: 8.775

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.