Christian A Gutschow1, Arnulf H Hölscher. 1. Department of General, Visceral, and Cancer Surgery, University of Cologne, Kerpener Strasse 62, 50931, Cologne, Germany. christian.gutschow@uk-koeln.de
Abstract
BACKGROUND: Gastroesophageal reflux disease is by far the most prevalent disorder of the foregut. For a long time during the twentieth century, surgical therapy was the mainstay of treatment and the only chance for cure for patients with severe symptoms. Later, after introduction of proton pump inhibitor therapy in the early 1990 s, surgical therapy was considered widely a second choice option due to its potential morbidity and side effects. More recently, however, there is growing evidence that long-term antisecretory therapy might be associated to a number of adverse effects such as osteoporosis and increased risk of cardiovascular events. This is the rationale why interventional and surgical options are coming back into focus. PURPOSE: The purpose of this review is to analyze and to discuss the current spectrum of surgical therapy of gastroesophageal reflux disease.
BACKGROUND:Gastroesophageal reflux disease is by far the most prevalent disorder of the foregut. For a long time during the twentieth century, surgical therapy was the mainstay of treatment and the only chance for cure for patients with severe symptoms. Later, after introduction of proton pump inhibitor therapy in the early 1990 s, surgical therapy was considered widely a second choice option due to its potential morbidity and side effects. More recently, however, there is growing evidence that long-term antisecretory therapy might be associated to a number of adverse effects such as osteoporosis and increased risk of cardiovascular events. This is the rationale why interventional and surgical options are coming back into focus. PURPOSE: The purpose of this review is to analyze and to discuss the current spectrum of surgical therapy of gastroesophageal reflux disease.
Authors: Francesco Volonté; Jean-Marie Collard; Louis Goncette; Christian Gutschow; Paolo Strignano Journal: Ann Thorac Surg Date: 2007-01 Impact factor: 4.330
Authors: S Mattioli; F D'Ovidio; M P Di Simone; F Bassi; S Brusori; V Pilotti; V Felice; L Ferruzzi; N Guernelli Journal: J Thorac Cardiovasc Surg Date: 1998-08 Impact factor: 5.209
Authors: Rudolf J Stadlhuber; Amr El Sherif; Sumeet K Mittal; Robert J Fitzgibbons; L Michael Brunt; John G Hunter; Tom R Demeester; Lee L Swanstrom; C Daniel Smith; Charles J Filipi Journal: Surg Endosc Date: 2008-12-06 Impact factor: 4.584