Literature DB >> 21121278

Nanomedicine-nanoscale drugs and delivery systems.

Surya Singh1.   

Abstract

Significant progress has been made in nanoscale drugs and delivery systems employing diverse chemical formulations to facilitate the rate of drug delivery and release from the human body. The biocompatible nanomaterials have been used in biological markers, contrast agents for biological imaging, healthcare products, pharmaceuticals, drug-delivery systems as well as in detection, diagnosis and treatment of various types of diseases. Nanomedicines offer delivery of potential drugs to human organs which were previously beyond reach of microscale drugs due to specific biological barriers. The nanoscale systems work as nanocarriers for the delivery of drugs. The nanocarriers are made of biocompatible and biodegradable materials such as synthetic proteins, peptides, lipids, polysaccharides, biodegradable polymers and fibers. This review article reports the recent developments in the field of nanomedicine covering biodegradable polymers, nanoparticles, cyclodextrin, dendrimeres, liposomes and lipid-based nanocarriers, nanofibers, nanowires and carbon nanotubes and their chemical functionalization for distribution to different organs, their solubility, surface, chemical and biological properties, stability and release systems. The toxicity and safety of nanomaterials on human health is also briefly discussed.

Entities:  

Mesh:

Year:  2010        PMID: 21121278     DOI: 10.1166/jnn.2010.3617

Source DB:  PubMed          Journal:  J Nanosci Nanotechnol        ISSN: 1533-4880


  21 in total

Review 1.  Nanotechnology-based drug delivery systems for targeting, imaging and diagnosis of neurodegenerative diseases.

Authors:  Sibel Bozdağ Pehlivan
Journal:  Pharm Res       Date:  2013-10       Impact factor: 4.200

Review 2.  The potential of magneto-electric nanocarriers for drug delivery.

Authors:  Ajeet Kaushik; Rahul Dev Jayant; Vidya Sagar; Madhavan Nair
Journal:  Expert Opin Drug Deliv       Date:  2014-07-02       Impact factor: 6.648

Review 3.  Safe clinical use of carbon nanotubes as innovative biomaterials.

Authors:  Naoto Saito; Hisao Haniu; Yuki Usui; Kaoru Aoki; Kazuo Hara; Seiji Takanashi; Masayuki Shimizu; Nobuyo Narita; Masanori Okamoto; Shinsuke Kobayashi; Hiroki Nomura; Hiroyuki Kato; Naoyuki Nishimura; Seiichi Taruta; Morinobu Endo
Journal:  Chem Rev       Date:  2014-04-10       Impact factor: 60.622

Review 4.  Lipid complexes with cationic peptides and OAKs; their role in antimicrobial action and in the delivery of antimicrobial agents.

Authors:  Raquel F Epand; Amram Mor; Richard M Epand
Journal:  Cell Mol Life Sci       Date:  2011-05-15       Impact factor: 9.261

5.  Carbon nanotubes linked with pitavastatin: synthesis and characterisation.

Authors:  E Borowiak-Palen; P Skupin; M Kruszynska; L Sobotta; J Mielcarek
Journal:  J Mater Sci Mater Med       Date:  2011-03-01       Impact factor: 3.896

6.  Engineering building blocks for self-assembling protein nanoparticles.

Authors:  Esther Vázquez; Antonio Villaverde
Journal:  Microb Cell Fact       Date:  2010-12-30       Impact factor: 5.328

7.  New surface radiolabeling schemes of super paramagnetic iron oxide nanoparticles (SPIONs) for biodistribution studies.

Authors:  Prakash D Nallathamby; Ninell P Mortensen; Heather A Palko; Mike Malfatti; Catherine Smith; James Sonnett; Mitchel J Doktycz; Baohua Gu; Ryan K Roeder; Wei Wang; Scott T Retterer
Journal:  Nanoscale       Date:  2015-04-21       Impact factor: 7.790

8.  Cell delivery of therapeutic nanoparticles.

Authors:  JoEllyn McMillan; Elena Batrakova; Howard E Gendelman
Journal:  Prog Mol Biol Transl Sci       Date:  2011       Impact factor: 3.622

9.  Activation of microbubbles by low-level therapeutic ultrasound enhances the antitumor effects of doxorubicin.

Authors:  Shuang Yang; Pan Wang; Xiaobing Wang; Xiaomin Su; Quanhong Liu
Journal:  Eur Radiol       Date:  2014-08-06       Impact factor: 5.315

10.  Biogenic green synthesis of monodispersed gum kondagogu (Cochlospermum gossypium) iron nanocomposite material and its application in germination and growth of mung bean (Vigna radiata) as a plant model.

Authors:  Dugyala Raju; Urmil J Mehta; Sashidhar Rao Beedu
Journal:  IET Nanobiotechnol       Date:  2016-06       Impact factor: 1.847

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