Literature DB >> 21119735

Genomics drugs in clinical trials.

Jonathan Hall, Patrick Dennler, Stephanie Haller, Anna Pratsinis, Katharina Säuberli, Harry Towbin, Katja Walther, Katja Walthe, Janine Woytschak.   

Abstract

Mesh:

Year:  2010        PMID: 21119735     DOI: 10.1038/nrd1552-c1

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  24 in total

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Journal:  Annu Rev Immunol       Date:  2001-12-19       Impact factor: 28.527

2.  The human genome at ten.

Authors: 
Journal:  Nature       Date:  2010-04-01       Impact factor: 49.962

Review 3.  Hurdles in the drug discovery of cathepsin K inhibitors.

Authors:  Motohiko Kometani; Kazuhiko Nonomura; Takashi Tomoo; Satoru Niwa
Journal:  Curr Top Med Chem       Date:  2010       Impact factor: 3.295

4.  TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease.

Authors:  J A Gross; J Johnston; S Mudri; R Enselman; S R Dillon; K Madden; W Xu; J Parrish-Novak; D Foster; C Lofton-Day; M Moore; A Littau; A Grossman; H Haugen; K Foley; H Blumberg; K Harrison; W Kindsvogel; C H Clegg
Journal:  Nature       Date:  2000-04-27       Impact factor: 49.962

5.  Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors.

Authors:  J P Sheridan; S A Marsters; R M Pitti; A Gurney; M Skubatch; D Baldwin; L Ramakrishnan; C L Gray; K Baker; W I Wood; A D Goddard; P Godowski; A Ashkenazi
Journal:  Science       Date:  1997-08-08       Impact factor: 47.728

6.  The receptor for the cytotoxic ligand TRAIL.

Authors:  G Pan; K O'Rourke; A M Chinnaiyan; R Gentz; R Ebner; J Ni; V M Dixit
Journal:  Science       Date:  1997-04-04       Impact factor: 47.728

7.  Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein.

Authors:  M E Brunkow; J C Gardner; J Van Ness; B W Paeper; B R Kovacevich; S Proll; J E Skonier; L Zhao; P J Sabo; Y Fu; R S Alisch; L Gillett; T Colbert; P Tacconi; D Galas; H Hamersma; P Beighton; J Mulligan
Journal:  Am J Hum Genet       Date:  2001-02-09       Impact factor: 11.025

Review 8.  Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy.

Authors:  Norma Lynn Fox; Robin Humphreys; Troy A Luster; Jerry Klein; Gilles Gallant
Journal:  Expert Opin Biol Ther       Date:  2010-01       Impact factor: 4.388

9.  Mutations of the BRAF gene in human cancer.

Authors:  Helen Davies; Graham R Bignell; Charles Cox; Philip Stephens; Sarah Edkins; Sheila Clegg; Jon Teague; Hayley Woffendin; Mathew J Garnett; William Bottomley; Neil Davis; Ed Dicks; Rebecca Ewing; Yvonne Floyd; Kristian Gray; Sarah Hall; Rachel Hawes; Jaime Hughes; Vivian Kosmidou; Andrew Menzies; Catherine Mould; Adrian Parker; Claire Stevens; Stephen Watt; Steven Hooper; Rebecca Wilson; Hiran Jayatilake; Barry A Gusterson; Colin Cooper; Janet Shipley; Darren Hargrave; Katherine Pritchard-Jones; Norman Maitland; Georgia Chenevix-Trench; Gregory J Riggins; Darell D Bigner; Giuseppe Palmieri; Antonio Cossu; Adrienne Flanagan; Andrew Nicholson; Judy W C Ho; Suet Y Leung; Siu T Yuen; Barbara L Weber; Hilliard F Seigler; Timothy L Darrow; Hugh Paterson; Richard Marais; Christopher J Marshall; Richard Wooster; Michael R Stratton; P Andrew Futreal
Journal:  Nature       Date:  2002-06-09       Impact factor: 49.962

10.  Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus.

Authors:  Richard Furie; William Stohl; Ellen M Ginzler; Michael Becker; Nilamadhab Mishra; Winn Chatham; Joan T Merrill; Arthur Weinstein; W Joseph McCune; John Zhong; Wendy Cai; William Freimuth
Journal:  Arthritis Res Ther       Date:  2008-09-11       Impact factor: 5.156

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  3 in total

Review 1.  Third-generation sequencing techniques and applications to drug discovery.

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Journal:  Expert Opin Drug Discov       Date:  2012-02-02       Impact factor: 6.098

Review 2.  Somatic variation and cancer: therapies lost in the mix.

Authors:  Andrew V Biankin; Thomas J Hudson
Journal:  Hum Genet       Date:  2011-06-05       Impact factor: 5.881

Review 3.  Unique roles of rare variants in the genetics of complex diseases in humans.

Authors:  Yukihide Momozawa; Keijiro Mizukami
Journal:  J Hum Genet       Date:  2020-09-18       Impact factor: 3.172

  3 in total

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