Literature DB >> 9242611

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors.

J P Sheridan1, S A Marsters, R M Pitti, A Gurney, M Skubatch, D Baldwin, L Ramakrishnan, C L Gray, K Baker, W I Wood, A D Goddard, P Godowski, A Ashkenazi.   

Abstract

TRAIL (also called Apo2L) belongs to the tumor necrosis factor family, activates rapid apoptosis in tumor cells, and binds to the death-signaling receptor DR4. Two additional TRAIL receptors were identified. The receptor designated death receptor 5 (DR5) contained a cytoplasmic death domain and induced apoptosis much like DR4. The receptor designated decoy receptor 1 (DcR1) displayed properties of a glycophospholipid-anchored cell surface protein. DcR1 acted as a decoy receptor that inhibited TRAIL signaling. Thus, a cell surface mechanism exists for the regulation of cellular responsiveness to pro-apoptotic stimuli.

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Year:  1997        PMID： 9242611     DOI： 10.1126/science.277.5327.818

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  388 in total

Review 1.  Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors.

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2.  TVB receptors for cytopathic and noncytopathic subgroups of avian leukosis viruses are functional death receptors.

Authors:  J Brojatsch; J Naughton; H B Adkins; J A Young
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

3.  Mechanisms of apoptosis.

Authors:  J C Reed
Journal:  Am J Pathol       Date:  2000-11       Impact factor: 4.307

4.  A fifteen-amino-acid TVB peptide serves as a minimal soluble receptor for subgroup B avian leukosis and sarcoma viruses.

Authors:  Daniel J Knauss; John A T Young
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

5.  Identification of death receptors DR4 and DR5 in HTB-12 astrocytoma cell lines and determination of TRAIL sensitivity.

Authors:  Elenia Riddick; Shavonda Evans; Jeffrey Rousch; Ephraim Gwebu; Hirendra Nath Banerjee
Journal:  J Solid Tumors       Date:  2013-12-01

6.  STAT3 Knockdown in B16 Melanoma by siRNA Lipopolyplexes Induces Bystander Immune Response In Vitro and In Vivo.

Authors:  Aws Alshamsan; Samar Hamdy; Azita Haddadi; John Samuel; Ayman O S El-Kadi; Hasan Uludağ; Afsaneh Lavasanifar
Journal:  Transl Oncol       Date:  2011-06-01       Impact factor: 4.243

7.  Anticancer activity of oncolytic adenovirus vector armed with IFN-alpha and ADP is enhanced by pharmacologically controlled expression of TRAIL.

Authors:  E V Shashkova; M N Kuppuswamy; W S M Wold; K Doronin
Journal:  Cancer Gene Ther       Date:  2007-11-09       Impact factor: 5.987

8.  Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells.

Authors:  Vassiliki Poulaki; Constantine S Mitsiades; Vassiliki Kotoula; Sophia Tseleni-Balafouta; Avi Ashkenazi; Demetrios A Koutras; Nicholas Mitsiades
Journal:  Am J Pathol       Date:  2002-08       Impact factor: 4.307

9.  Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5.

Authors:  Tai-Guang Jin; Alexei Kurakin; Nordine Benhaga; Karon Abe; Mehrdad Mohseni; Ferry Sandra; Keli Song; Brian K Kay; Roya Khosravi-Far
Journal:  J Biol Chem       Date:  2004-10-14       Impact factor: 5.157

Review 10.  Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand.

Authors:  Nor Saadah M Azahri; Mary M Kavurma
Journal:  Cell Mol Life Sci       Date:  2013-01-18       Impact factor: 9.261
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