| Literature DB >> 21119699 |
Abstract
Most of the molecular mechanisms contributing to long-term memory have been found to consolidate information within a brief time window after learning, but not to maintain information during memory storage. However, with the discovery that synaptic long-term potentiation is maintained by the persistently active protein kinase, protein kinase Mζ (PKMζ), a possible mechanism of memory storage has been identified. Recent research shows how PKMζ might perpetuate information both at synapses and during long-term memory.Entities:
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Year: 2010 PMID: 21119699 DOI: 10.1038/nrn2949
Source DB: PubMed Journal: Nat Rev Neurosci ISSN: 1471-003X Impact factor: 34.870