Literature DB >> 21115283

Coping with DNA double strand breaks.

Kevin Hiom1.   

Abstract

The repair of DNA double strand breaks (dsb) is important for maintaining the physical and genetic integrity of the genome. Moreover, in humans it is associated with the prevention of diseases such as immune deficiencies and cancer. This review briefly explores the fundamental strategies for repairing dsb, examines how cells maximize the fidelity of dsb repair in the cell cycle and discusses the requirements for dsb repair in the context of chromatin.
Copyright © 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 21115283     DOI: 10.1016/j.dnarep.2010.09.018

Source DB:  PubMed          Journal:  DNA Repair (Amst)        ISSN: 1568-7856


  49 in total

1.  ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair.

Authors:  Jean-Yves Bleuyard; Rémi Buisson; Jean-Yves Masson; Fumiko Esashi
Journal:  EMBO Rep       Date:  2012-02-01       Impact factor: 8.807

2.  A role for homologous recombination proteins in cell cycle regulation.

Authors:  Kaja Kostyrko; Sandra Bosshard; Zuzanna Urban; Nicolas Mermod
Journal:  Cell Cycle       Date:  2015-06-30       Impact factor: 4.534

Review 3.  Variants of core histones and their roles in cell fate decisions, development and cancer.

Authors:  Marcus Buschbeck; Sandra B Hake
Journal:  Nat Rev Mol Cell Biol       Date:  2017-02-01       Impact factor: 94.444

Review 4.  The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Authors:  Yosef Shiloh; Yael Ziv
Journal:  Nat Rev Mol Cell Biol       Date:  2013-03-13       Impact factor: 94.444

5.  Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.

Authors:  Birgit Debrabant; Mette Soerensen; Friederike Flachsbart; Serena Dato; Jonas Mengel-From; Tinna Stevnsner; Vilhelm A Bohr; Torben A Kruse; Stefan Schreiber; Almut Nebel; Kaare Christensen; Qihua Tan; Lene Christiansen
Journal:  Eur J Hum Genet       Date:  2014-02-12       Impact factor: 4.246

Review 6.  Combined Treatment Modalities for High-Energy Proton Irradiation: Exploiting Specific DNA Repair Dependencies.

Authors:  Simon Deycmar; Martin Pruschy
Journal:  Int J Part Ther       Date:  2018-09-21

Review 7.  Microbial antigenic variation mediated by homologous DNA recombination.

Authors:  Cornelis Vink; Gloria Rudenko; H Steven Seifert
Journal:  FEMS Microbiol Rev       Date:  2012-01-17       Impact factor: 16.408

Review 8.  Epigenetic regulation of genomic integrity.

Authors:  Angela K Deem; Xuan Li; Jessica K Tyler
Journal:  Chromosoma       Date:  2012-01-17       Impact factor: 4.316

Review 9.  Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer.

Authors:  Shanbeh Zienolddiny; Vidar Skaug
Journal:  Lung Cancer (Auckl)       Date:  2011-12-29

Review 10.  From yeast to mammals: recent advances in genetic control of homologous recombination.

Authors:  Yoav Karpenshif; Kara A Bernstein
Journal:  DNA Repair (Amst)       Date:  2012-08-11
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