Literature DB >> 21114680

A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control.

Panagiotis A Koromantzos1, Konstantinos Makrilakis, Xanthippi Dereka, Nicholas Katsilambros, Ioannis A Vrotsos, Phoebus N Madianos.   

Abstract

AIM: the purpose of the present study was to assess the effect of non-surgical periodontal therapy on glycaemic control of type 2 diabetes patients with moderate-to-severe periodontitis.
MATERIALS AND METHODS: this was a randomized, controlled clinical trial of patients with type 2 diabetes. A total of 60 patients with moderate-to-severe periodontal disease were assigned to either a periodontal treatment arm, consisting of scaling and root planing (intervention group [IG]), or a delayed treatment arm that received periodontal care after 6 months (control group [CG]). Periodontal parameters and glycosylated haemoglobin (A1C) were evaluated at 1, 3 and 6 months.
RESULTS: all periodontal parameters improved significantly in the IG. A1C levels decreased statistically significantly more in the IG versus the CG (0.72%versus 0.13%; p<0.01) independently of other confounders.
CONCLUSIONS: this study provides evidence that periodontal treatment contributes to improved glycaemic control in type 2 diabetes mellitus patients. Larger controlled trials are needed to confirm if this finding is generalizable to other populations of patients with type 2 diabetes.

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Year:  2010        PMID: 21114680     DOI: 10.1111/j.1600-051X.2010.01652.x

Source DB:  PubMed          Journal:  J Clin Periodontol        ISSN: 0303-6979            Impact factor:   8.728


  43 in total

Review 1.  Effect of nonsurgical periodontal treatment on glycosylated hemoglobin in diabetic patients: a systematic review.

Authors:  Elisabet Mauri-Obradors; Enric Jané-Salas; Maria del Mar Sabater-Recolons; Miguel Vinas; José López-López
Journal:  Odontology       Date:  2014-07-26       Impact factor: 2.634

2.  Nonsurgical periodontal therapy with/without diode laser modulates metabolic control of type 2 diabetics with periodontitis: a randomized clinical trial.

Authors:  Emrah Koçak; Mehmet Sağlam; Seyit Ali Kayış; Niyazi Dündar; Levent Kebapçılar; Bruno G Loos; Sema S Hakkı
Journal:  Lasers Med Sci       Date:  2016-01-11       Impact factor: 3.161

3.  Effect of nonsurgical periodontal therapy (with or without oral doxycycline delivery) on glycemic status and clinical periodontal parameters in patients with prediabetes: a short-term longitudinal randomized case-control study.

Authors:  Fawad Javed; Hameeda Bashir Ahmed; Abid Mehmood; Crawford Bain; Georgios E Romanos
Journal:  Clin Oral Investig       Date:  2014-01-22       Impact factor: 3.573

Review 4.  Diabetes mellitus and periodontitis: a tale of two common interrelated diseases.

Authors:  Evanthia Lalla; Panos N Papapanou
Journal:  Nat Rev Endocrinol       Date:  2011-06-28       Impact factor: 43.330

5.  The effect of periodontal therapy on glycaemic control in a Hispanic population with type 2 diabetes: a randomized controlled trial.

Authors:  Isabel C Gay; Duong T Tran; Adriana C Cavender; Robin Weltman; Jennifer Chang; Estelle Luckenbach; Gena D Tribble
Journal:  J Clin Periodontol       Date:  2014-06-01       Impact factor: 8.728

Review 6.  Management of diabolical diabetes mellitus and periodontitis nexus: Are we doing enough?

Authors:  Abhijit N Gurav
Journal:  World J Diabetes       Date:  2016-02-25

7.  Photobiomodulation for the treatment of periodontal pockets in patients with type 2 diabetes: 1-year results of a randomized clinical trial.

Authors:  Nídia Castro Dos Santos; Naira M R B Andere; Manuela Maria Viana Miguel; Lúcio Murilo Dos Santos; Milton Santamaria; Ingrid Fernandes Mathias; Maria Aparecida Neves Jardini; Mauro Pedrine Santamaria
Journal:  Lasers Med Sci       Date:  2019-05-15       Impact factor: 3.161

8.  Local adjunct effect of antimicrobial photodynamic therapy for the treatment of chronic periodontitis in type 2 diabetics: split-mouth double-blind randomized controlled clinical trial.

Authors:  Nídia Cristina Castro Dos Santos; Naira Maria Rebelatto Bechara Andere; Cássia Fernandes Araujo; Andrea Carvalho de Marco; Lúcio Murilo Dos Santos; Maria Aparecida Neves Jardini; Mauro Pedrine Santamaria
Journal:  Lasers Med Sci       Date:  2016-07-22       Impact factor: 3.161

9.  The virtual dental home: implications for policy and strategy.

Authors:  Paul Glassman; Maureen Harrington; Elizabeth Mertz; Maysa Namakian
Journal:  J Calif Dent Assoc       Date:  2012-07

Review 10.  Evidence that periodontal treatment improves diabetes outcomes: a systematic review and meta-analysis.

Authors:  Steven Engebretson; Thomas Kocher
Journal:  J Periodontol       Date:  2013-04       Impact factor: 6.993

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