Literature DB >> 26962409

Management of diabolical diabetes mellitus and periodontitis nexus: Are we doing enough?

Abhijit N Gurav1.   

Abstract

Periodontitis is the commonest oral disease affecting population worldwide. This disease is notorious for the devastation of tooth supporting structures, ensuing in the loss of dentition. The etiology for this disease is bacterial biofilm, which accumulates on the teeth as dental plaque. In addition to the biofilm microorganisms, other factors such as environmental, systemic and genetic are also responsible in progression of periodontitis. Diabetes mellitus (DM) is metabolic disorder which has an impact on the global health. DM plays a crucial role in the pathogenesis of periodontitis. Periodontitis is declared as the "sixth" major complication of DM. Evidence based literature has depicted an enhanced incidence and severity of periodontitis in subjects with DM. A "two way" relationship has been purported between periodontitis and DM. Mutual management of both conditions is necessary. Periodontal therapy (PT) may assist to diminish the progression of DM and improve glycemic control. Various advanced technological facilities may be utilized for the purpose of patient education and disease management. The present paper clarifies the etio-pathogenesis of periodontitis, establishing it as a complication of DM and elaborating the various mechanisms involved in the pathogenesis. The role of PT in amelioration of DM and application of digital communication will be discussed. Overall, it is judicious to create an increased patient cognizance of the periodontitis-DM relationship. Conjunctive efforts must be undertaken by the medical and oral health care professionals for the management of periodontitis affected DM patients.

Entities:  

Keywords:  Advanced glycation end products; Complications; Cost-effectiveness; Glycated hemoglobin; Inflammation; Mobile health; Periodontal therapy; Periodontitis; Scaling and root planing; Type 2 diabetes mellitus

Year:  2016        PMID: 26962409      PMCID: PMC4766246          DOI: 10.4239/wjd.v7.i4.50

Source DB:  PubMed          Journal:  World J Diabetes        ISSN: 1948-9358


  230 in total

1.  Multi-center intervention study on glycohemoglobin (HbA1c) and serum, high-sensitivity CRP (hs-CRP) after local anti-infectious periodontal treatment in type 2 diabetic patients with periodontal disease.

Authors:  S Katagiri; H Nitta; T Nagasawa; I Uchimura; H Izumiyama; K Inagaki; T Kikuchi; T Noguchi; M Kanazawa; A Matsuo; H Chiba; N Nakamura; N Kanamura; S Inoue; I Ishikawa; Y Izumi
Journal:  Diabetes Res Clin Pract       Date:  2009-01-24       Impact factor: 5.602

Review 2.  Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis.

Authors:  Despoina Vasilakou; Thomas Karagiannis; Eleni Athanasiadou; Maria Mainou; Aris Liakos; Eleni Bekiari; Maria Sarigianni; David R Matthews; Apostolos Tsapas
Journal:  Ann Intern Med       Date:  2013-08-20       Impact factor: 25.391

Review 3.  What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome?

Authors:  Giovanni Tarantino; Carmine Finelli
Journal:  World J Gastroenterol       Date:  2013-06-14       Impact factor: 5.742

4.  Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes.

Authors:  Silvio E Inzucchi; Richard M Bergenstal; John B Buse; Michaela Diamant; Ele Ferrannini; Michael Nauck; Anne L Peters; Apostolos Tsapas; Richard Wender; David R Matthews
Journal:  Diabetes Care       Date:  2015-01       Impact factor: 19.112

5.  The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects.

Authors:  A Promsudthi; S Pimapansri; C Deerochanawong; W Kanchanavasita
Journal:  Oral Dis       Date:  2005-09       Impact factor: 3.511

6.  Dose-response relationship between periodontal inflamed surface area and HbA1c in type 2 diabetics.

Authors:  Willem Nesse; Annemiek Linde; Frank Abbas; Frederik Karst Lucien Spijkervet; Pieter Ubele Dijkstra; Eric Carl de Brabander; Izzy Gerstenbluth; Arjan Vissink
Journal:  J Clin Periodontol       Date:  2009-03-11       Impact factor: 8.728

7.  Impact of different periodontitis case definitions on periodontal research.

Authors:  Fernando O Costa; Alessandra N Guimarães; Luís O M Cota; André L Pataro; Takeshi K Segundo; Sheila C Cortelli; José E Costa
Journal:  J Oral Sci       Date:  2009-06       Impact factor: 1.556

8.  Smartphone-enabled health coach intervention for people with diabetes from a modest socioeconomic strata community: single-arm longitudinal feasibility study.

Authors:  Noah Wayne; Paul Ritvo
Journal:  J Med Internet Res       Date:  2014-06-06       Impact factor: 5.428

9.  SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria.

Authors:  Yukihiro Chino; Yoshishige Samukawa; Soichi Sakai; Yasuhiro Nakai; Jun-ichi Yamaguchi; Takeo Nakanishi; Ikumi Tamai
Journal:  Biopharm Drug Dispos       Date:  2014-08-06       Impact factor: 1.627

10.  Study of TNF-α, IL-1β and LPS levels in the gingival crevicular fluid of a rat model of diabetes mellitus and periodontitis.

Authors:  Zhu-Ling Jiang; Yu-Qiong Cui; Rui Gao; Ying Li; Zhao-Chen Fu; Bin Zhang; Cheng-Chao Guan
Journal:  Dis Markers       Date:  2013       Impact factor: 3.434

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  6 in total

1.  [Research progress on the relationship and mechanisms between periodontal disease and preterm birth and low-birth-weight infants].

Authors:  Wu Wanhong; Ye Changchang; Huang Ping
Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi       Date:  2017-10-01

2.  [Expression of high mobility group protein B1 in periodontal tissues and its association with hepatic lipid metabolism in diabetic rats with periodontitis].

Authors:  Xinfo Pei; Shu Meng; Ce Gou; Qin Du
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2020-01-30

3.  Advanced glycosylated end products restrain the osteogenic differentiation of the periodontal ligament stem cell.

Authors:  Zhu-Ling Guo; Shan-Ling Gan; Chun-Yi Cao; Rao Fu; Sheng-Ping Cao; Chen Xie; Jing-Wei Chen; Alex Gibson; Xu Zheng; Nai-Chia Teng
Journal:  J Dent Sci       Date:  2019-04-16       Impact factor: 2.080

4.  Quantification of TNF-α in Patients with Periodontitis and Type 2 Diabetes.

Authors:  Víctor M Martínez-Aguilar; Bertha A Carrillo-Ávila; Eduardo A Sauri-Esquivel; Eugenia Guzmán-Marín; Matilde Jiménez-Coello; Diana María Escobar-García; Amaury Pozos-Guillén
Journal:  Biomed Res Int       Date:  2019-07-04       Impact factor: 3.411

Review 5.  Pathogenic Molecular Mechanisms in Periodontitis and Peri-Implantitis: Role of Advanced Glycation End Products.

Authors:  Grigorios Plemmenos; Christina Piperi
Journal:  Life (Basel)       Date:  2022-01-30

6.  Correlation Analysis of miR-1246 Expression in Saliva of Patients with Chronic Periodontitis and Periodontal Indexes, Inflammatory Cytokines, and Protease Molecules.

Authors:  Shuainan Wu; Zhaobao Li; Jianqi Wang; Lu Liu; Ying Pang
Journal:  Evid Based Complement Alternat Med       Date:  2022-07-30       Impact factor: 2.650

  6 in total

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