Literature DB >> 2111336

Clinical use of the determination of serotonin in whole blood.

H P Kremer1, J G Goekoop, G M Van Kempen.   

Abstract

Whole blood serotonin (5-hydroxytryptamine, 5-HT) was assayed, and factors possibly influencing 5-HT content were investigated in healthy controls. No significant circadian rhythm or effect of dexamethasone or meals was observed. After use of fluvoxamine, a specific 5-HT reuptake inhibitor, the whole-blood 5-HT concentration of patients was strongly reduced. After treatment with tranylcypromine, an unspecific monoamine oxidase inhibitor (MAOI), the 5-HT content was increased. Determination of whole blood 5-HT in patients treated with fluvoxamine presents a measure of drug compliance. Furthermore, the method may have clinical potential for finding an adequate dose when a 5-HT reuptake inhibitor or an MAOI is used.

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Year:  1990        PMID： 2111336     DOI： 10.1097/00004714-199004000-00002

Source DB:  PubMed          Journal:  J Clin Psychopharmacol        ISSN： 0271-0749            Impact factor:   3.153


  6 in total

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Authors:  Borwin Bandelow; David Baldwin; Marianna Abelli; Blanca Bolea-Alamanac; Michel Bourin; Samuel R Chamberlain; Eduardo Cinosi; Simon Davies; Katharina Domschke; Naomi Fineberg; Edna Grünblatt; Marek Jarema; Yong-Ku Kim; Eduard Maron; Vasileios Masdrakis; Olya Mikova; David Nutt; Stefano Pallanti; Stefano Pini; Andreas Ströhle; Florence Thibaut; Matilde M Vaghi; Eunsoo Won; Dirk Wedekind; Adam Wichniak; Jade Woolley; Peter Zwanzger; Peter Riederer
Journal:  World J Biol Psychiatry       Date:  2016-07-15       Impact factor: 4.132

2.  beta-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo.

Authors:  W Pirker; S Asenbaum; S Kasper; H Walter; P Angelberger; G Koch; A Pozzera; L Deecke; I Podreka; T Brücke
Journal:  J Neural Transm Gen Sect       Date:  1995

3.  Depression and whole blood serotonin in patients with coronary heart disease from the Heart and Soul Study.

Authors:  Lawson R Wulsin; Dominique Musselman; Christian Otte; Erica Bruce; Sadia Ali; Mary A Whooley
Journal:  Psychosom Med       Date:  2009-03-17       Impact factor: 4.312

4.  Peripheral serotoninergic response to physical exercise in athletic horses.

Authors:  Daniela Alberghina; Claudia Giannetto; Giuseppe Piccione
Journal:  J Vet Sci       Date:  2010-12       Impact factor: 1.672

5.  Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation.

Authors:  Masanori Asada; Satoru Ebihara; Shinsuke Yamanda; Kaijun Niu; Tatsuma Okazaki; Ichiro Sora; Hiroyuki Arai
Journal:  Neoplasia       Date:  2009-04       Impact factor: 5.715

6.  The role of platelet serotonin and depression in the acute coronary syndrome population.

Authors:  Jennifer E Sanner; Lorraine Frazier; Malini Udtha
Journal:  Yale J Biol Med       Date:  2013-03-12
  6 in total

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