Literature DB >> 21109916

Predictive value of resting heart rate for cardiovascular and all-cause mortality.

Jaqueline Eilert Fagundes1, Iran Castro.   

Abstract

BACKGROUND: Resting heart rate (which ranges from 60 to 80 bpm) is one of the simplest cardiovascular parameters, and has been considered as a predictor of cardiovascular and all-cause mortality.
OBJECTIVE: To determine the predictive value of resting heart rate (RHR) before exercise stress testing (ET) for cardiovascular (CV) and all-cause mortality.
METHODS: This was a case-control study using data from the database of the Exercise Testing Laboratory of a cardiac hospital and the death records of the Health Department of a city located in the South of Brazil from January 1995 to June 2007. A total of 7,055 patients were studied; 1,645 (23.3%) in the case group (deceased) and 5,410 (76.7%) in the control group (alive). The cut-off value of RHR for mortality was derived from the ROC curve, and a multivariate analysis was performed for the selected variables. The study's outcome measures were cardiovascular and all-cause mortality.
RESULTS: Six hundred and seventy-four patients died of cardiovascular diseases (9.5%); the cut-off value was RHR ≥ 78 bpm). After adjusting for selected variables, the odds ratio (OR) of RHR ≥ 78 bpm was 3.5 (95% CI 2.9 to 4.2) for CV mortality and 3.6 (95% CI 3.2 to 4.0) for all-cause mortality.
CONCLUSION: Resting heart rate ≥ 78 is an independent predictor of cardiovascular and all-cause mortality.

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Year:  2010        PMID: 21109916     DOI: 10.1590/s0066-782x2010005000149

Source DB:  PubMed          Journal:  Arq Bras Cardiol        ISSN: 0066-782X            Impact factor:   2.000


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