Literature DB >> 21103494

Aptamer-based turn-on fluorescent four-branched quaternary ammonium pyrazine probe for selective thrombin detection.

Shengyong Yan1, Rong Huang, Yangyang Zhou, Ming Zhang, Minggang Deng, Xiaolin Wang, Xiaocheng Weng, Xiang Zhou.   

Abstract

In this thrombin detection system, the bright fluorescence of TASPI is almost eliminated by the DNA aptamer TBA (turn-off); however, in the presence of thrombin, it specifically binds to TBA by folding unrestricted TBA into an anti-parallel G-quadruplex structure and then releasing TASPI molecules, resulting in vivid and facile fluorescence recovery (turn-on).

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Year:  2010        PMID： 21103494     DOI： 10.1039/c0cc02792h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

Review 1.  G-quadruplexes for luminescent sensing and logic gates.

Authors:  Hong-Zhang He; Daniel Shiu-Hin Chan; Chung-Hang Leung; Dik-Lung Ma
Journal:  Nucleic Acids Res       Date:  2013-02-23       Impact factor: 16.971

2.  (E,E,E,E)-2,3,5,6-Tetra-kis{2-[4-(dimethyl-amino)-phen-yl]ethen-yl}pyrazine.

Authors:  Volker Schmitt; Dieter Schollmeyer; Heiner Detert
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-05-28

3.  Detection of Thrombin Based on Fluorescence Energy Transfer between Semiconducting Polymer Dots and BHQ-Labelled Aptamers.

Authors:  Yizhang Liu; Xuekai Jiang; Wenfeng Cao; Junyong Sun; Feng Gao
Journal:  Sensors (Basel)       Date:  2018-02-14       Impact factor: 3.576

4.  A Non-Label and Enzyme-Free Sensitive Detection Method for Thrombin Based on Simulation-Assisted DNA Assembly.

Authors:  Yingying Zhang; Luhui Wang; Yanan Wang; Yafei Dong
Journal:  Sensors (Basel)       Date:  2018-07-06       Impact factor: 3.576

5.  Impact of the Position of the Chemically Modified 5-Furyl-2'-Deoxyuridine Nucleoside on the Thrombin DNA Aptamer-Protein Complex: Structural Insights into Aptamer Response from MD Simulations.

Authors:  Preethi Seelam Prabhakar; Richard A Manderville; Stacey D Wetmore
Journal:  Molecules       Date:  2019-08-10       Impact factor: 4.411

Review 6.  G-quadruplex-based aptamers against protein targets in therapy and diagnostics.

Authors:  Chiara Platella; Claudia Riccardi; Daniela Montesarchio; Giovanni N Roviello; Domenica Musumeci
Journal:  Biochim Biophys Acta Gen Subj       Date:  2016-11-16       Impact factor: 3.770

7.  An Enzyme- and Label-Free Fluorescence Aptasensor for Detection of Thrombin Based on Graphene Oxide and G-Quadruplex.

Authors:  Yani Wei; Luhui Wang; Yingying Zhang; Yafei Dong
Journal:  Sensors (Basel)       Date:  2019-10-12       Impact factor: 3.576

8.  Selective recognition of parallel and anti-parallel thrombin-binding aptamer G-quadruplexes by different fluorescent dyes.

Authors:  Dan Zhao; Xiongwei Dong; Nan Jiang; Dan Zhang; Changlin Liu
Journal:  Nucleic Acids Res       Date:  2014-09-22       Impact factor: 16.971

Review 9.  Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics.

Authors:  Domenica Musumeci; Chiara Platella; Claudia Riccardi; Federica Moccia; Daniela Montesarchio
Journal:  Cancers (Basel)       Date:  2017-12-20       Impact factor: 6.639
  9 in total

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