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Literature DB >> 21096883

Real-time experiment interface for biological control applications.

Risa J Lin¹, Jonathan Bettencourt, John Wha Ite, David J Christini, Robert J Butera.

Abstract

The Real-time Experiment Interface (RTXI) is a fast and versatile real-time biological experimentation system based on Real-Time Linux. RTXI is open source and free, can be used with an extensive range of experimentation hardware, and can be run on Linux or Windows computers (when using the Live CD). RTXI is currently used extensively for two experiment types: dynamic patch clamp and closed-loop stimulation pattern control in neural and cardiac single cell electrophysiology. RTXI includes standard plug-ins for implementing commonly used electrophysiology protocols with synchronized stimulation, event detection, and online analysis. These and other user-contributed plug-ins can be found on the website (http://www.rtxi.org).

Entities: Chemical Disease Species

Mesh：

Year: 2010 PMID： 21096883 PMCID： PMC3647344 DOI： 10.1109/IEMBS.2010.5627397

Source DB: PubMed Journal: Annu Int Conf IEEE Eng Med Biol Soc ISSN： 2375-7477

10 in total

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2. Real-Time linux dynamic clamp: a fast and flexible way to construct virtual ion channels in living cells.

Authors: A D Dorval; D J Christini; J A White
Journal: Ann Biomed Eng Date: 2001-10 Impact factor: 3.934

3. MRCI: a flexible real-time dynamic clamp system for electrophysiology experiments.

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Authors: N D Schiff; J T Giacino; K Kalmar; J D Victor; K Baker; M Gerber; B Fritz; B Eisenberg; T Biondi; J O'Connor; E J Kobylarz; S Farris; A Machado; C McCagg; F Plum; J J Fins; A R Rezai
Journal: Nature Date: 2007-08-02 Impact factor: 49.962

5. Control of electrical alternans in canine cardiac purkinje fibers.

Authors: David J Christini; Mark L Riccio; Calin A Culianu; Jeffrey J Fox; Alain Karma; Robert F Gilmour
Journal: Phys Rev Lett Date: 2006-03-17 Impact factor: 9.161

6. Effects of imperfect dynamic clamp: computational and experimental results.

Authors: Jonathan C Bettencourt; Kyle P Lillis; Laura R Stupin; John A White
Journal: J Neurosci Methods Date: 2007-10-24 Impact factor: 2.390

Review 7. The NEURON simulation environment.

Authors: M L Hines; N T Carnevale
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8. Controlling chaos in the brain.

Authors: S J Schiff; K Jerger; D H Duong; T Chang; M L Spano; W L Ditto
Journal: Nature Date: 1994-08-25 Impact factor: 49.962

9. Dynamical mechanism for subcellular alternans in cardiac myocytes.

Authors: Stephen A Gaeta; Gil Bub; Geoffrey W Abbott; David J Christini
Journal: Circ Res Date: 2009-07-23 Impact factor: 17.367

10. Anthropomorphizing the mouse cardiac action potential via a novel dynamic clamp method.

Authors: Rebecca C Ahrens-Nicklas; David J Christini
Journal: Biophys J Date: 2009-11-18 Impact factor: 4.033

10 in total

28 in total

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2. Open Ephys electroencephalography (Open Ephys + EEG): a modular, low-cost, open-source solution to human neural recording.

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3. Dynamic clamp in cardiac and neuronal systems using RTXI.

Authors: Francis A Ortega; Robert J Butera; David J Christini; John A White; Alan D Dorval
Journal: Methods Mol Biol Date: 2014

4. Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance.

Authors: Joseph L Ransdell; Edward Dranoff; Brandon Lau; Wan-Lin Lo; David L Donermeyer; Paul M Allen; Jeanne M Nerbonne
Journal: Cell Rep Date: 2017-04-18 Impact factor: 9.423

5. Voltage and calcium dynamics both underlie cellular alternans in cardiac myocytes.

Authors: Willemijn Groenendaal; Francis A Ortega; Trine Krogh-Madsen; David J Christini
Journal: Biophys J Date: 2014-05-20 Impact factor: 4.033

6. Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1^G93A Mouse Model for ALS.

Authors: Soju Seki; Toru Yamamoto; Kiara Quinn; Igor Spigelman; Antonios Pantazis; Riccardo Olcese; Martina Wiedau-Pazos; Scott H Chandler; Sharmila Venugopal
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7. Stochastic slowly adapting ionic currents may provide a decorrelation mechanism for neural oscillators by causing wander in the intrinsic period.

Authors: Sharon E Norman; Robert J Butera; Carmen C Canavier
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