BACKGROUND: Analysis of myocardial deformation from data stored in Digital Imaging and Communications in Medicine format using vendor-independent software may be useful for clinical and research purposes but has not been evaluated in children. METHODS: Grayscale images were prospectively acquired on Vivid 7 (GE Healthcare) and iE33 (Philips Medical Systems) ultrasound systems in 49 children. Digital Imaging and Communications in Medicine and raw data were analyzed using vendor-independent software (Cardiac Performance Analysis, Tomtec Imaging Systems) and vendor-specific software (EchoPAC and QLAB) and results compared. In addition, vendor-independent software using images at 30 frames/sec were compared with images at the higher acquisition frame rate. RESULTS: Measurement of short-axis radial and circumferential strain (ε) and apical four-chamber longitudinal ε by vendor-independent software was possible in >92% of the children. Intraobserver and interobserver coefficients of variation for global circumferential and longitudinal ε ranged from 7.1% to 15.3% and for radial ε from 23.9% to 30.2%. Strain values were somewhat higher when using GE images at acquisition frame rates compared with ε values using GE images stored at 30 frames/sec. Strain values obtained by vendor-independent software were comparable with those obtained by vendor-specific software for longitudinal ε and higher for circumferential ε. Radial ε values obtained by vendor-independent software were lower than ε values by EchoPAC and higher than ε values by QLAB. CONCLUSIONS: Vendor-independent software-derived ε is feasible and potentially valuable for measuring myocardial deformation in research and in multicenter studies using images from different ultrasound systems, especially for longitudinal deformation. However, a systematic bias for circumferential ε and a high variability in radial ε measurements remain concerns.
BACKGROUND: Analysis of myocardial deformation from data stored in Digital Imaging and Communications in Medicine format using vendor-independent software may be useful for clinical and research purposes but has not been evaluated in children. METHODS: Grayscale images were prospectively acquired on Vivid 7 (GE Healthcare) and iE33 (Philips Medical Systems) ultrasound systems in 49 children. Digital Imaging and Communications in Medicine and raw data were analyzed using vendor-independent software (Cardiac Performance Analysis, Tomtec Imaging Systems) and vendor-specific software (EchoPAC and QLAB) and results compared. In addition, vendor-independent software using images at 30 frames/sec were compared with images at the higher acquisition frame rate. RESULTS: Measurement of short-axis radial and circumferential strain (ε) and apical four-chamber longitudinal ε by vendor-independent software was possible in >92% of the children. Intraobserver and interobserver coefficients of variation for global circumferential and longitudinal ε ranged from 7.1% to 15.3% and for radial ε from 23.9% to 30.2%. Strain values were somewhat higher when using GE images at acquisition frame rates compared with ε values using GE images stored at 30 frames/sec. Strain values obtained by vendor-independent software were comparable with those obtained by vendor-specific software for longitudinal ε and higher for circumferential ε. Radial ε values obtained by vendor-independent software were lower than ε values by EchoPAC and higher than ε values by QLAB. CONCLUSIONS: Vendor-independent software-derived ε is feasible and potentially valuable for measuring myocardial deformation in research and in multicenter studies using images from different ultrasound systems, especially for longitudinal deformation. However, a systematic bias for circumferential ε and a high variability in radial ε measurements remain concerns.
Authors: Philip Thaler Levy; Mark R Holland; Timothy J Sekarski; Aaron Hamvas; Gautam K Singh Journal: J Am Soc Echocardiogr Date: 2013-07-20 Impact factor: 5.251
Authors: Philip T Levy; Aliza Machefsky; Aura A Sanchez; Meghna D Patel; Sarah Rogal; Susan Fowler; Lauren Yaeger; Angela Hardi; Mark R Holland; Aaron Hamvas; Gautam K Singh Journal: J Am Soc Echocardiogr Date: 2015-12-30 Impact factor: 5.251
Authors: Suma P Goudar; G Hamilton Baker; Shahryar M Chowdhury; Kimberly J Reid; Girish Shirali; Mark A Scheurer Journal: Echocardiography Date: 2016-10-14 Impact factor: 1.724
Authors: Philip T Levy; Aura A Sanchez Mejia; Aliza Machefsky; Susan Fowler; Mark R Holland; Gautam K Singh Journal: J Am Soc Echocardiogr Date: 2014-02-26 Impact factor: 5.251