R S Choung1, M E Branda, D Chitkara, N D Shah, S K Katusic, G R Locke, N J Talley. 1. Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA. Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. University of North Carolina Center for Functional GI and Motility Disorders, Chapel Hill, NC, USA. Department of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Abstract
BACKGROUND: Although direct medical costs for constipation-related medical visits are thought to be high, to date, there have been no studies examining longitudinal resource utilisation in adults with constipation. AIM: To estimate the incremental direct medical costs associated with constipation in women. METHODS: This is a nested case-control study. The study population consisted of all mothers of 5718 children in the population-based birth cohort born during 1976-1982 in a community. The cases presented to the medical facilities with constipation. The controls were randomly selected and matched to cases in a 2:1 ratio. Direct medical costs for constipated women and controls were collected for the years 1987-2002. RESULTS: We identified 168 women with a diagnosis of constipation. The total direct medical costs over the 15-year period for constipated subjects were more than double those of controls [$63 591 (95% CI: 49 786-81 396) vs. $24 529 (95% CI: 20 667-29 260)]. The overall out-patient costs for constipated women were $38 897 (95% CI: 31 381-48 253) compared to $15 110 (95% CI: 12 904-17 781) for controls. The median of annual out-patient visits for constipated women was 0.16 compared to 0.11 for controls. CONCLUSION: Women with constipation have significantly higher medical care utilisation and expenditures compared with women without constipation.
BACKGROUND: Although direct medical costs for constipation-related medical visits are thought to be high, to date, there have been no studies examining longitudinal resource utilisation in adults with constipation. AIM: To estimate the incremental direct medical costs associated with constipation in women. METHODS: This is a nested case-control study. The study population consisted of all mothers of 5718 children in the population-based birth cohort born during 1976-1982 in a community. The cases presented to the medical facilities with constipation. The controls were randomly selected and matched to cases in a 2:1 ratio. Direct medical costs for constipatedwomen and controls were collected for the years 1987-2002. RESULTS: We identified 168 women with a diagnosis of constipation. The total direct medical costs over the 15-year period for constipated subjects were more than double those of controls [$63 591 (95% CI: 49 786-81 396) vs. $24 529 (95% CI: 20 667-29 260)]. The overall out-patient costs for constipatedwomen were $38 897 (95% CI: 31 381-48 253) compared to $15 110 (95% CI: 12 904-17 781) for controls. The median of annual out-patient visits for constipatedwomen was 0.16 compared to 0.11 for controls. CONCLUSION:Women with constipation have significantly higher medical care utilisation and expenditures compared with women without constipation.
Authors: Denesh K Chitkara; Nicholas J Talley; Amy L Weaver; Slavica K Katusic; Heiko De Schepper; Mary Jo Rucker; G Richard Locke Journal: Clin Gastroenterol Hepatol Date: 2006-08-08 Impact factor: 11.382
Authors: Nicholas J Shaheen; Richard A Hansen; Douglas R Morgan; Lisa M Gangarosa; Yehuda Ringel; Michelle T Thiny; Mark W Russo; Robert S Sandler Journal: Am J Gastroenterol Date: 2006-07-18 Impact factor: 10.864
Authors: D A Drossman; Z Li; E Andruzzi; R D Temple; N J Talley; W G Thompson; W E Whitehead; J Janssens; P Funch-Jensen; E Corazziari Journal: Dig Dis Sci Date: 1993-09 Impact factor: 3.199