Literature DB >> 16901769

Incidence of presentation of common functional gastrointestinal disorders in children from birth to 5 years: a cohort study.

Denesh K Chitkara1, Nicholas J Talley, Amy L Weaver, Slavica K Katusic, Heiko De Schepper, Mary Jo Rucker, G Richard Locke.   

Abstract

BACKGROUND & AIMS: Gastroesophageal reflux disease (GERD), abdominal pain of unknown origin, and constipation are thought to be causes for frequent medical visits during childhood. The aim of this study was to estimate the incidences, repeat presentation, clinical symptoms, and sociodemographic risk factors in children who medically presented for GERD, abdominal pain of unknown origin, and constipation from birth to 5 years.
METHODS: This was a population-based, retrospective birth cohort study of all children born to mothers residing in Rochester, Minnesota who remained in the area until at least age 5 (n = 5718). The medical records of all individuals were searched for relevant diagnostic billing codes for GERD, abdominal pain of unknown origin, and constipation, without another underlying diagnosis, and manually reviewed. Parental sociodemographic factors collected from birth certificate records on patients and matched controls were compared.
RESULTS: The incidence for childhood (age, <5 y) presentation of GERD, abdominal pain of unknown origin, and constipation was .9/1000 person-years, 4.5/1000 person-years, and 6.8/1000 person-years, respectively; there were no significant differences between boys and girls. Three or more medical visits by age 5 occurred in 11%, 19%, and 24% of children who were seen for abdominal pain of unknown origin, constipation, and GERD, respectively. Single parentage, maternal age (<18 y), and maternal education (<high school) were not associated with abdominal pain or constipation presentation.
CONCLUSIONS: The incidences of presentation for GERD, abdominal pain of unknown origin, and constipation are among the highest for pediatric disorders, and a cause for repeated medical consultations.

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Year:  2006        PMID: 16901769     DOI: 10.1016/j.cgh.2006.06.012

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN: 1542-3565            Impact factor:   11.382


  9 in total

1.  Direct medical costs of constipation from childhood to early adulthood: a population-based birth cohort study.

Authors:  Rok Seon Choung; Nilay D Shah; Denesh Chitkara; Megan E Branda; Miranda A Van Tilburg; William E Whitehead; Slavica K Katusic; G Richard Locke; Nicholas J Talley
Journal:  J Pediatr Gastroenterol Nutr       Date:  2011-01       Impact factor: 2.839

2.  Longitudinal direct medical costs associated with constipation in women.

Authors:  R S Choung; M E Branda; D Chitkara; N D Shah; S K Katusic; G R Locke; N J Talley
Journal:  Aliment Pharmacol Ther       Date:  2010-11-22       Impact factor: 8.171

Review 3.  Management of functional abdominal pain and irritable bowel syndrome in children and adolescents.

Authors:  Eric Chiou; Samuel Nurko
Journal:  Expert Rev Gastroenterol Hepatol       Date:  2010-06       Impact factor: 3.869

4.  Esomeprazole for the treatment of erosive esophagitis in children: an international, multicenter, randomized, parallel-group, double-blind (for dose) study.

Authors:  Vasundhara Tolia; Nader N Youssef; Mark A Gilger; Barry Traxler; Marta Illueca
Journal:  BMC Pediatr       Date:  2010-06-11       Impact factor: 2.125

Review 5.  Colonic transit studies: normal values for adults and children with comparison of radiological and scintigraphic methods.

Authors:  Bridget R Southwell; Melanie C C Clarke; Jonathan Sutcliffe; John M Hutson
Journal:  Pediatr Surg Int       Date:  2009-06-02       Impact factor: 1.827

6.  Fecal Lactoferrin: Reliable Biomarker for Intestinal Inflammation in Pediatric IBD.

Authors:  Stephan Buderus; James H Boone; Michael J Lentze
Journal:  Gastroenterol Res Pract       Date:  2015-05-24       Impact factor: 2.260

Review 7.  Gastrointestinal symptoms associated with gastroesophageal reflux disease, and their relapses after treatment with proton pump inhibitors: A systematic review.

Authors:  Mousalreza Hosseini; Roshanak Salari; Somayeh Shariatmaghani; Batul Birjandi; Masoumeh Salari
Journal:  Electron Physician       Date:  2017-06-25

8.  Childhood constipation: Current status, challenges, and future perspectives.

Authors:  Shaman Rajindrajith; Niranga Manjuri Devanarayana; Marc A Benninga
Journal:  World J Clin Pediatr       Date:  2022-09-09

9.  Clinical Characteristics of Children Needing Inpatient Treatment after Failed Outpatient Treatment for Fecal Impaction.

Authors:  Amrita Sinha; Maroun Mhanna; Reema Gulati
Journal:  Pediatr Gastroenterol Hepatol Nutr       Date:  2018-06-28
  9 in total

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