PURPOSE: To evaluate which is the minimum number of oocytes to be allocated to each recipient in a shared egg donor program. METHODS: We analyzed 953 recipients that received at least 4 metaphase II (MII) oocytes in the period 2006-2008. We retrospectively divided the recipients according to the number of MII oocytes actually received. RESULTS: No statistically significant differences were found among the analyzed strata in clinical pregnancy rate (A:43.7%; B:45.6%; C:48.6%; D:45.5%; E:53%, P=NS) and miscarriage rate. However, the rate of top quality transferred embryos, and the embryo freezing rate were significantly higher among those recipients that received 7 or more mature eggs. CONCLUSIONS: After a large sample was analyzed, no significant differences in fresh embryo transfer outcome were encountered when a different number of oocytes was allocated. A minimum of 4 MII oocytes seems to achieve satisfactory pregnancy rates in our shared egg donor program.
PURPOSE: To evaluate which is the minimum number of oocytes to be allocated to each recipient in a shared egg donor program. METHODS: We analyzed 953 recipients that received at least 4 metaphase II (MII) oocytes in the period 2006-2008. We retrospectively divided the recipients according to the number of MII oocytes actually received. RESULTS: No statistically significant differences were found among the analyzed strata in clinical pregnancy rate (A:43.7%; B:45.6%; C:48.6%; D:45.5%; E:53%, P=NS) and miscarriage rate. However, the rate of top quality transferred embryos, and the embryo freezing rate were significantly higher among those recipients that received 7 or more mature eggs. CONCLUSIONS: After a large sample was analyzed, no significant differences in fresh embryo transfer outcome were encountered when a different number of oocytes was allocated. A minimum of 4 MII oocytes seems to achieve satisfactory pregnancy rates in our shared egg donor program.
Authors: J E Buster; M Bustillo; I Thorneycroft; J A Simon; S P Boyers; J R Marshall; R G Seed; J A Louw Journal: Lancet Date: 1983-04-09 Impact factor: 79.321
Authors: M Bustillo; J E Buster; S W Cohen; F Hamilton; I H Thorneycroft; J A Simon; I A Rodi; S P Boyers; J R Marshall; J A Louw Journal: JAMA Date: 1984-02-17 Impact factor: 56.272
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Authors: D Navot; N Laufer; J Kopolovic; R Rabinowitz; A Birkenfeld; A Lewin; M Granat; E J Margalioth; J G Schenker Journal: N Engl J Med Date: 1986-03-27 Impact factor: 91.245
Authors: Efstratios M Kolibianakis; Herman Tournaye; Kaan Osmanagaoglu; Michel Camus; Linda Van Waesberghe; Andre Van Steirteghem; Paul Devroey Journal: Fertil Steril Date: 2003-01 Impact factor: 7.329