OBJECTIVES: To compare the amount of newly formed bone after sinus floor augmentation with two different particle sizes of bovine bone mineral (BBM) using clinical, micro-computerized tomography (CT) and histological techniques. METHODS: Bilateral sinus floor augmentations were performed in 10 patients. Six to 9 months later, bone samples were retrieved and analyzed. RESULTS: Results: Both groups were not different in vertical bone height achieved after augmentation, post-operative complications and maximal torque for the insertion of implants. Micro-CT measurements could not detect a statistically significant difference in bone volume between the groups (with a tendency for new more bone in the small granules group). Histomorphometric analysis revealed that both granule sizes produced the same pattern of bone formation, surrounding the graft granules, and producing a shape of a network, "bridging" between the BBM particles. Multi-nucleated giant cells, probably osteoclasts, were observed directly on the BBM particle surface in both groups. The osteoclast-like cells preferred the small-size BBM particles and not the large particles both in the small-size and the large-size granules group. CONCLUSION: Both sizes of BBM granules preformed equally and achieved the aim of the sinus floor augmentation procedure clinically and histologically.
RCT Entities:
OBJECTIVES: To compare the amount of newly formed bone after sinus floor augmentation with two different particle sizes of bovine bone mineral (BBM) using clinical, micro-computerized tomography (CT) and histological techniques. METHODS: Bilateral sinus floor augmentations were performed in 10 patients. Six to 9 months later, bone samples were retrieved and analyzed. RESULTS: Results: Both groups were not different in vertical bone height achieved after augmentation, post-operative complications and maximal torque for the insertion of implants. Micro-CT measurements could not detect a statistically significant difference in bone volume between the groups (with a tendency for new more bone in the small granules group). Histomorphometric analysis revealed that both granule sizes produced the same pattern of bone formation, surrounding the graft granules, and producing a shape of a network, "bridging" between the BBM particles. Multi-nucleated giant cells, probably osteoclasts, were observed directly on the BBM particle surface in both groups. The osteoclast-like cells preferred the small-size BBM particles and not the large particles both in the small-size and the large-size granules group. CONCLUSION: Both sizes of BBM granules preformed equally and achieved the aim of the sinus floor augmentation procedure clinically and histologically.
Authors: Eleni Kapogianni; Mike Barbeck; Tim Fienitz; Daniel Rothamel; Ole Jung; Aylin Arslan; Lennart Kuhnel; Xin Xiong; Rumen Krastev; Reinhard E. Friedrich; Reinhard Schnettler Journal: In Vivo Date: 2019 Nov-Dec Impact factor: 2.155
Authors: Margherita Tumedei; Eitan Mijiritsky; Carlos Fernando Mourão; Adriano Piattelli; Marco Degidi; Carlo Mangano; Giovanna Iezzi Journal: Int J Environ Res Public Health Date: 2022-06-28 Impact factor: 4.614
Authors: Amir Reza Rokn; Mohammad Amin Khodadoostan; Amir Ali Reza Rasouli Ghahroudi; Puria Motahhary; Mohammad Javad Kharrazi Fard; Hugo De Bruyn; Rose Afzalifar; Ehsan Soolar; Ahmad Soolari Journal: Open Dent J Date: 2011-07-07