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Literature DB >> 21083245

Human microdosing for the prediction of patient response.

Paul T Henderson, Chong-Xian Pan.

Abstract

Entities: CellLine Chemical Disease Gene Species

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Year: 2010 PMID： 21083245 PMCID： PMC3113695 DOI： 10.4155/bio.10.3

Source DB: PubMed Journal: Bioanalysis ISSN： 1757-6180 Impact factor: 2.681

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22 in total

Review 1. Microdosing: a valuable tool for accelerating drug development and the role of bioanalytical methods in meeting the challenge.

Authors: Robert M J Ings
Journal: Bioanalysis Date: 2009-10 Impact factor: 2.681

2. Characterization of oxaliplatin-DNA adduct formation in DNA and differentiation of cancer cell drug sensitivity at microdose concentrations.

Authors: Sang Soo Hah; Rhoda A Sumbad; Ralph W de Vere White; Kenneth W Turteltaub; Paul T Henderson
Journal: Chem Res Toxicol Date: 2007-11-15 Impact factor: 3.739

3. Application of liquid chromatography-accelerator mass spectrometry (LC-AMS) to evaluate the metabolic profiles of a drug candidate in human urine and plasma.

Authors: Chandra Prakash; Christopher L Shaffer; Larry M Tremaine; Rosa G Liberman; Paul L Skipper; Jimmy Flarakos; Steven R Tannenbaum
Journal: Drug Metab Lett Date: 2007-08

Review 4. Biomedical accelerator mass spectrometry: recent applications in metabolism and pharmacokinetics.

Authors: Graham Lappin; Lloyd Stevens
Journal: Expert Opin Drug Metab Toxicol Date: 2008-08 Impact factor: 4.481

5. Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B(1) pharmacokinetics in human volunteers.

Authors: Carole Jubert; John Mata; Graham Bench; Roderick Dashwood; Cliff Pereira; William Tracewell; Kenneth Turteltaub; David Williams; George Bailey
Journal: Cancer Prev Res (Phila) Date: 2009-12-01

6. Dose-response relationships for N7-(2-hydroxyethyl)guanine induced by low-dose [14C]ethylene oxide: evidence for a novel mechanism of endogenous adduct formation.

Authors: Debbie A Marsden; Donald J L Jones; Robert G Britton; Ted Ognibene; Esther Ubick; George E Johnson; Peter B Farmer; Karen Brown
Journal: Cancer Res Date: 2009-03-10 Impact factor: 12.701

7. Evaluation of microdosing strategies for studies in preclinical drug development: demonstration of linear pharmacokinetics in dogs of a nucleoside analog over a 50-fold dose range.

Authors: Punam Sandhu; John S Vogel; Mark J Rose; Esther A Ubick; Janice E Brunner; Michael A Wallace; Jennifer K Adelsberger; Maribeth P Baker; Paul T Henderson; Paul G Pearson; Thomas A Baillie
Journal: Drug Metab Dispos Date: 2004-07-30 Impact factor: 3.922

8. Integration of continuous-flow accelerator mass spectrometry with chromatography and mass-selective detection.

Authors: Jimmy Flarakos; Rosa G Liberman; Steven R Tannenbaum; Paul L Skipper
Journal: Anal Chem Date: 2008-05-22 Impact factor: 6.986

9. An interface for direct analysis of (14)c in nonvolatile samples by accelerator mass spectrometry.

Authors: Rosa G Liberman; Steven R Tannenbaum; Barbara J Hughey; Ruth E Shefer; Robert E Klinkowstein; Chandra Prakash; Shawn P Harriman; Paul L Skipper
Journal: Anal Chem Date: 2004-01-15 Impact factor: 6.986

Review 10. Setting the stage for tailored chemotherapy in the management of non-small cell lung cancer.

Authors: George R Simon; Mubeena Begum; Gerold Bepler
Journal: Future Oncol Date: 2008-02 Impact factor: 3.404

11 in total

Review 1. Quantifying exploratory low dose compounds in humans with AMS.

Authors: Stephen R Dueker; Le T Vuong; Peter N Lohstroh; Jason A Giacomo; John S Vogel
Journal: Adv Drug Deliv Rev Date: 2010-10-31 Impact factor: 15.470

Review 2. Phase 0/microdosing approaches: time for mainstream application in drug development?

Authors: Tal Burt; Graeme Young; Wooin Lee; Hiroyuki Kusuhara; Oliver Langer; Malcolm Rowland; Yuichi Sugiyama
Journal: Nat Rev Drug Discov Date: 2020-09-08 Impact factor: 84.694

3. The biodistribution and pharmacokinetics of the oxime acetylcholinesterase reactivator RS194B in guinea pigs.

Authors: Michael A Malfatti; Heather A Enright; Nicholas A Be; Edward A Kuhn; Saphon Hok; M Windy McNerney; Victoria Lao; Tuan H Nguyen; Felice C Lightstone; Timothy S Carpenter; Brian J Bennion; Carlos A Valdez
Journal: Chem Biol Interact Date: 2017-09-21 Impact factor: 5.192

4. COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin.

Authors: Fuli Wang; Hongyong Zhang; Ai-Hong Ma; Weimin Yu; Maike Zimmermann; Jun Yang; Sung Hee Hwang; Daniel Zhu; Tzu-Yin Lin; Michael Malfatti; Kenneth W Turteltaub; Paul T Henderson; Susan Airhart; Bruce D Hammock; Jianlin Yuan; Ralph W de Vere White; Chong-Xian Pan
Journal: Mol Cancer Ther Date: 2017-12-28 Impact factor: 6.261