Literature DB >> 21080630

SIRT1 modulation as a novel approach to the treatment of diseases of aging.

Charles A Blum1, James L Ellis, Christine Loh, Pui Yee Ng, Robert B Perni, Ross L Stein.   

Abstract

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Year:  2010        PMID： 21080630     DOI： 10.1021/jm100861p

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  24 in total

Review 1.  Sirtuins in neurodegenerative diseases: a biological-chemical perspective.

Authors:  Aparna Raghavan; Zahoor A Shah
Journal:  Neurodegener Dis       Date:  2011-10-28       Impact factor: 2.977

2.  A mechanism-based potent sirtuin inhibitor containing Nε-thiocarbamoyl-lysine (TuAcK).

Authors:  Brett M Hirsch; Yujun Hao; Xiaopeng Li; Chrys Wesdemiotis; Zhenghe Wang; Weiping Zheng
Journal:  Bioorg Med Chem Lett       Date:  2011-06-22       Impact factor: 2.823

Review 3.  Sirtuin catalysis and regulation.

Authors:  Jessica L Feldman; Kristin E Dittenhafer-Reed; John M Denu
Journal:  J Biol Chem       Date:  2012-10-18       Impact factor: 5.157

4.  Pharmacologic stimulation of cytochrome P450 46A1 and cerebral cholesterol turnover in mice.

Authors:  Natalia Mast; Yong Li; Marlin Linger; Matthew Clark; Jeffrey Wiseman; Irina A Pikuleva
Journal:  J Biol Chem       Date:  2013-12-18       Impact factor: 5.157

Review 5.  Lysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulation.

Authors:  Michael W Van Dyke
Journal:  ChemMedChem       Date:  2014-01-21       Impact factor: 3.466

6.  Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man.

Authors:  Ethan Hoffmann; Jeff Wald; Siva Lavu; John Roberts; Claire Beaumont; Jon Haddad; Peter Elliott; Christoph Westphal; Eric Jacobson
Journal:  Br J Clin Pharmacol       Date:  2013-01       Impact factor: 4.335

Review 7.  Germline energetics, aging, and female infertility.

Authors:  Jonathan L Tilly; David A Sinclair
Journal:  Cell Metab       Date:  2013-06-04       Impact factor: 27.287

Review 8.  Small molecule SIRT1 activators for the treatment of aging and age-related diseases.

Authors:  Basil P Hubbard; David A Sinclair
Journal:  Trends Pharmacol Sci       Date:  2014-01-16       Impact factor: 14.819

Review 9.  The sirtuin family's role in aging and age-associated pathologies.

Authors:  Jessica A Hall; John E Dominy; Yoonjin Lee; Pere Puigserver
Journal:  J Clin Invest       Date:  2013-03-01       Impact factor: 14.808

10.  Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1.

Authors:  Marina M Bellet; Yasukazu Nakahata; Mohamed Boudjelal; Emma Watts; Danuta E Mossakowska; Kenneth A Edwards; Marlene Cervantes; Giuseppe Astarita; Christine Loh; James L Ellis; George P Vlasuk; Paolo Sassone-Corsi
Journal:  Proc Natl Acad Sci U S A       Date:  2013-01-22       Impact factor: 11.205
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