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Literature DB >> 21079593

Grand challenge commentary: Synthetic immunology to engineer human immunity.

Abstract

Rationally designing new strategies to control the human immune response stands as a key challenge for the scientific community. Chemical biologists have the opportunity to address specific issues in this area that have important implications for both basic science and clinical medicine.

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Year: 2010 PMID： 21079593 DOI： 10.1038/nchembio.477

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

20 in total

1. A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules.

Authors: James W Nelson; Alexander G Chamessian; Patrick J McEnaney; Ryan P Murelli; Barbara I Kazmierczak; Barbara I Kazmiercak; David A Spiegel
Journal: ACS Chem Biol Date: 2010-10-05 Impact factor: 5.100

Review 2. Nuclear reprogramming to a pluripotent state by three approaches.

Authors: Shinya Yamanaka; Helen M Blau
Journal: Nature Date: 2010-06-10 Impact factor: 49.962

Review 3. Evolution of induced pluripotent stem cell technology.

Authors: Hongyan Zhou; Sheng Ding
Journal: Curr Opin Hematol Date: 2010-07 Impact factor: 3.284

4. A synthetic vaccine consisting of a tumor-associated sialyl-T(N)-MUC1 tandem-repeat glycopeptide and tetanus toxoid: induction of a strong and highly selective immune response.

Authors: Anton Kaiser; Nikola Gaidzik; Ulrika Westerlind; Danuta Kowalczyk; Alexandra Hobel; Edgar Schmitt; Horst Kunz
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

Review 5. Development of antibody surrogates for the treatment of cancers and autoimmune disease.

Authors: Thomas Kodadek
Journal: Curr Opin Chem Biol Date: 2010-07-31 Impact factor: 8.822

Review 6. Bacteriophages and cancer.

Authors: Paulina Budynek; Krystyna Dabrowska; Grzegorz Skaradziński; Andrzej Górski
Journal: Arch Microbiol Date: 2010-03-16 Impact factor: 2.552

7. Optimized clostridium-directed enzyme prodrug therapy improves the antitumor activity of the novel DNA cross-linking agent PR-104.

Authors: Shie-Chau Liu; G-One Ahn; Mitomu Kioi; Mary-Jo Dorie; Adam V Patterson; J Martin Brown
Journal: Cancer Res Date: 2008-10-01 Impact factor: 12.701

8. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.

Authors: César Cobaleda; Wolfram Jochum; Meinrad Busslinger
Journal: Nature Date: 2007-09-12 Impact factor: 49.962

Review 9. Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.

Authors: Philip S Low; Walter A Henne; Derek D Doorneweerd
Journal: Acc Chem Res Date: 2007-07-27 Impact factor: 22.384

Review 10. Synthetic carbohydrate-based anticancer vaccines: the Memorial Sloan-Kettering experience.

Authors: Jianglong Zhu; J David Warren; Samuel J Danishefsky
Journal: Expert Rev Vaccines Date: 2009-10 Impact factor: 5.217

11 in total

Review 1. Multi-target drugs to address multiple checkpoints in complex inflammatory pathologies: evolutionary cues for novel "first-in-class" anti-inflammatory drug candidates: a reviewer's perspective.

Authors: Geetha Mathew; M K Unnikrishnan
Journal: Inflamm Res Date: 2015-07-18 Impact factor: 4.575

10. Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System.

Authors: Hsiao-Tieh Hsu; Brian M Trantow; Robert M Waymouth; Paul A Wender
Journal: Bioconjug Chem Date: 2015-09-25 Impact factor: 4.774

Grand challenge commentary: Synthetic immunology to engineer human immunity.

1. A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules.

Review 2. Nuclear reprogramming to a pluripotent state by three approaches.

Review 3. Evolution of induced pluripotent stem cell technology.

4. A synthetic vaccine consisting of a tumor-associated sialyl-T(N)-MUC1 tandem-repeat glycopeptide and tetanus toxoid: induction of a strong and highly selective immune response.

Review 5. Development of antibody surrogates for the treatment of cancers and autoimmune disease.

Review 6. Bacteriophages and cancer.

7. Optimized clostridium-directed enzyme prodrug therapy improves the antitumor activity of the novel DNA cross-linking agent PR-104.

8. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.

Review 9. Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.

Review 10. Synthetic carbohydrate-based anticancer vaccines: the Memorial Sloan-Kettering experience.

Review 1. Multi-target drugs to address multiple checkpoints in complex inflammatory pathologies: evolutionary cues for novel "first-in-class" anti-inflammatory drug candidates: a reviewer's perspective.

2. Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators.

3. Reprogramming urokinase into an antibody-recruiting anticancer agent.

Review 4. Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease.

Review 5. Glycomaterials for probing host-pathogen interactions and the immune response.

Review 6. Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities.

7. Stimulation of innate immune cells by light-activated TLR7/8 agonists.

8. Chemically synthesized molecules with the targeting and effector functions of antibodies.

9. Multifunctional Glycoconjugates for Recruiting Natural Antibodies against Cancer Cells.

10. Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System.