BACKGROUND: The incidence of ductal carcinoma in situ (DCIS) has increased substantially in the western world in recent decades. The aim of this study was to investigate the incidence according to grade distribution, age, and implementation of a population-based screening programme. METHODS: Cases of primary pure DCIS (n = 3167) were obtained from the Cancer Registry of Norway. Poisson regression was used to estimate trends in incidence. RESULTS: Age-adjusted incidence of DCIS increased from 4 to 11 per 100, 000 women-years from 1993 to 2007, in parallel with the implementation of screening. Higher incidence was observed among prevalent (IRR 3.3) and subsequent (IRR 2.8) invited women compared with those not invited. The proportion of DCIS among breast malignancies increased throughout the period, most markedly in the age range of screening. CONCLUSION: The increased proportion of DCIS during the study period is probably due to improved diagnostics resulting from the implementation of population-based screening.
BACKGROUND: The incidence of ductal carcinoma in situ (DCIS) has increased substantially in the western world in recent decades. The aim of this study was to investigate the incidence according to grade distribution, age, and implementation of a population-based screening programme. METHODS: Cases of primary pure DCIS (n = 3167) were obtained from the Cancer Registry of Norway. Poisson regression was used to estimate trends in incidence. RESULTS: Age-adjusted incidence of DCIS increased from 4 to 11 per 100, 000 women-years from 1993 to 2007, in parallel with the implementation of screening. Higher incidence was observed among prevalent (IRR 3.3) and subsequent (IRR 2.8) invited women compared with those not invited. The proportion of DCIS among breast malignancies increased throughout the period, most markedly in the age range of screening. CONCLUSION: The increased proportion of DCIS during the study period is probably due to improved diagnostics resulting from the implementation of population-based screening.
Authors: Solveig Hofvind; Per Skaane; Joann G Elmore; Sofie Sebuødegård; Solveig Roth Hoff; Christoph I Lee Journal: Radiology Date: 2014-04-01 Impact factor: 11.105
Authors: Lars J Grimm; Marc D Ryser; Ann H Partridge; Alastair M Thompson; Jeremy S Thomas; Jelle Wesseling; E Shelley Hwang Journal: Ann Surg Oncol Date: 2017-08-09 Impact factor: 5.344
Authors: Elsebeth Lynge; Antonio Ponti; Ted James; Ondřej Májek; My von Euler-Chelpin; Ahti Anttila; Patricia Fitzpatrick; Alfonso Frigerio; Masaaki Kawai; Astrid Scharpantgen; Mireille Broeders; Solveig Hofvind; Carmen Vidal; Maria Ederra; Dolores Salas; Jean-Luc Bulliard; Mariano Tomatis; Karla Kerlikowske; Stephen Taplin Journal: Eur J Cancer Date: 2013-09-13 Impact factor: 9.162
Authors: Maria Gloria Luciani; Junhee Seok; Aejaz Sayeed; Stacey Champion; William H Goodson; Stefanie S Jeffrey; Wenzhong Xiao; Michael Mindrinos; Ronald W Davis; Shanaz H Dairkee Journal: PLoS One Date: 2011-05-19 Impact factor: 3.240