Literature DB >> 21067928

Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents.

B V Subba Reddy1, M Ramana Reddy, Ch Madan, K Pranay Kumar, M Srinivasa Rao.   

Abstract

Three-component coupling of aldehyde, indole and kojic acid has been achieved using a catalytic amount of InCl(3) under solvent free conditions to produce a novel series of 2-substituted aryl(indolyl)kojic acid derivatives in good yields and with high selectivity. These compounds are found to exhibit potent antifungal properties.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 21067928     DOI： 10.1016/j.bmcl.2010.10.003

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Green synthesis of some 3-(α,α-diarylmethyl)indoles by bio-nanocomposite from embedding L-histidinium trichloroacetate ionic liquid on functionalized magnetite (L-His+CCl3CO2-@PEG@SiO2-nano Fe3O4).

Authors:  Kobra Nikoofar; Narges Saheb Ekhtiari
Journal:  Mol Divers       Date:  2021-07-23       Impact factor: 2.943

2.  Enhancement of commercial antifungal agents by Kojic Acid.

Authors:  Jong H Kim; Perng-Kuang Chang; Kathleen L Chan; Natália C G Faria; Noreen Mahoney; Young K Kim; Maria de L Martins; Bruce C Campbell
Journal:  Int J Mol Sci       Date:  2012-10-26       Impact factor: 5.923

3.  Synergism of antifungal activity between mitochondrial respiration inhibitors and kojic acid.

Authors:  Jong H Kim; Bruce C Campbell; Kathleen L Chan; Noreen Mahoney; Ronald P Haff
Journal:  Molecules       Date:  2013-01-25       Impact factor: 4.411
  3 in total

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